論文 - 詳細
| RRC ID | 839 |
|---|---|
| 著者 | Nishimura R, Hayashi M, Wu GJ, Kouchi H, Imaizumi-Anraku H, Murakami Y, Kawasaki S, Akao S, Ohmori M, Nagasawa M, Harada K, Kawaguchi M. |
| タイトル | HAR1 mediates systemic regulation of symbiotic organ development. |
| ジャーナル | Nature |
| Abstract |
Symbiotic root nodules are beneficial to leguminous host plants; however, excessive nodulation damages the host because it interferes with the distribution of nutrients in the plant. To keep a steady balance, the nodulation programme is regulated systemically in leguminous hosts. Leguminous mutants that have lost this ability display a hypernodulating phenotype. Through the use of reciprocal and self-grafting studies using Lotus japonicus hypernodulating mutants, har1 (also known as sym78), we show that the shoot genotype is responsible for the negative regulation of nodule development. A map-based cloning strategy revealed that HAR1 encodes a protein with a relative molecular mass of 108,000, which contains 21 leucine-rich repeats, a single transmembrane domain and serine/threonine kinase domains. The har1 mutant phenotype was rescued by transfection of the HAR1 gene. In a comparison of Arabidopsis receptor-like kinases, HAR1 showed the highest level of similarity with CLAVATA1 (CLV1). CLV1 negatively regulates formation of the shoot and floral meristems through cell-cell communication involving the CLV3 peptide. Identification of hypernodulation genes thus indicates that genes in leguminous plants bearing a close resemblance to CLV1 regulate nodule development systemically, by means of organ-organ communication. |
| 巻・号 | 420(6914) |
| ページ | 426-9 |
| 公開日 | 2002-11-28 |
| DOI | 10.1038/nature01231 |
| PII | nature01231 |
| PMID | 12442172 |
| MeSH | Arabidopsis Proteins / chemistry Arabidopsis Proteins / genetics Chromosome Mapping Cloning, Molecular DNA, Plant / analysis DNA, Plant / genetics Genes, Plant / genetics Genetic Complementation Test Lotus / enzymology* Lotus / genetics Lotus / growth & development* Lotus / metabolism Molecular Sequence Data Mutation / genetics Nitrogen Fixation* Plant Roots / enzymology Plant Roots / genetics Plant Roots / growth & development Plant Roots / metabolism Plant Shoots / enzymology Plant Shoots / genetics Plant Shoots / metabolism Protein Serine-Threonine Kinases / chemistry Protein Serine-Threonine Kinases / genetics Protein Serine-Threonine Kinases / metabolism* RNA, Plant / analysis RNA, Plant / genetics Receptor Protein-Tyrosine Kinases / chemistry Receptor Protein-Tyrosine Kinases / genetics Signal Transduction Soybeans / chemistry Soybeans / genetics Symbiosis* Transplants |
| IF | 42.779 |
| 引用数 | 355 |
| WOS 分野 | PLANT SCIENCES |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | F1000Research |
| 各媒体での言及数の合計 | 9 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ミヤコグサ・ダイズ | Gifu B-129 Miyakojima MG-20 |