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  • Search Condition : Filter (MeSH = Receptor Protein-Tyrosine Kinases / genetics)
Species Resource Title
C.intestinalis / (O.japonicus) Wild C. int Cionin, a vertebrate cholecystokinin/gastrin homolog, induces ovulation in the ascidian Ciona intestinalis type A.
Human and Animal Cells KU-YS(RCB1318) , SK-N-SH(RCB0426) , TNB1(RCB0481) , KP-N-NS(RCB0687) Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.
Human and Animal Cells 32D(RCB1145) In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
Drosophila 13780R-2 , 13781R-1 Coordination among multiple receptor tyrosine kinase signals controls Drosophila developmental timing and body size.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3.
Human and Animal Cells UE6E7T-2(RCB2153) Expression of beclin-1 in the microenvironment of invasive ductal carcinoma of the breast: correlation with prognosis and the cancer-stromal interaction.
C.elegans tm737 , tm1210 , tm311 Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor.
Drosophila DGRC#103970 Amalgam regulates the receptor tyrosine kinase pathway through Sprouty in glial cell development in the Drosophila larval brain.
Human and Animal Cells TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) , TGBC1TKB(RCB1129) , TGBC2TKB(RCB1130) miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer.
Human and Animal Cells TE-5(RCB1949) , TE-6(RCB1950) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells.
Human and Animal Cells Ba/F3(RCB0805) , 32D(RCB1145) Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain.
Human and Animal Cells PC-9(RCB4455) Osimertinib Overcomes Alectinib Resistance Caused by Amphiregulin in a Leptomeningeal Carcinomatosis Model of ALK-Rearranged Lung Cancer.
C.elegans tm737 C. elegans Tensin Promotes Axon Regeneration by Linking the Met-like SVH-2 and Integrin Signaling Pathways.
Human and Animal Cells TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF.
Drosophila The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila.
Human and Animal Cells PC-9(RCB4455) AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells.
Human and Animal Cells TE-5(RCB1949) , TE-6(RCB1950) , TE-10(RCB2099) , TE-14(RCB2101) Biphasic regulation of tumorigenesis by PTK7 expression level in esophageal squamous cell carcinoma.
C.elegans tm748 Distinct roles of the RasGAP family proteins in C. elegans associative learning and memory.
Human and Animal Cells PC-9(RCB4455) Tumor-suppressive effect of LRIG1, a negative regulator of ErbB, in non-small cell lung cancer harboring mutant EGFR.
Human and Animal Cells TE-5(RCB1949) , TE-9(RCB1988) PTK7 is a novel oncogenic target for esophageal squamous cell carcinoma.