論文 - 詳細
| RRC ID | 84808 |
|---|---|
| 著者 | Yoshikawa S, Itaya K, Hoshina R, Tashiro Y, Suda W, Cho Y, Matsuura M, Shindo C, Ito T, Hattori M, Miyamoto H, Kodama H. |
| タイトル | Thermophile-fermented feed modulates the gut microbiota related to lactate metabolism in pigs. |
| ジャーナル | J Appl Microbiol |
| Abstract |
AIMS:Extracts of fermented feed obtained via fermentation of marine animal resources with thermophilic Bacillaceae bacteria increase the fecundity of livestock. The intestinal bacterial profiles in response to long-term administration of this extract to pigs were investigated. METHODS AND RESULTS:Half of a swine farm was supplied with potable water containing an extract of fermented feed for more than 2 years, whereas the other half was supplied with potable water without the extract. Feces from 6-month-old pigs rearing in these two areas were collected. 16S rRNA gene sequencing and isolation of lactic acid bacteria revealed an increase in the D/L-lactate-producing bacterium, Lactobacillus amylovorus, and a decrease in several members of Clostridiales following administration of fermented feed. A lactate-utilizing bacterium, Megasphaera elsdenii, was more abundant in the feces of pigs in the fermented feed group. All representative isolates of M. elsdenii showed rapid utilization of D-lactate relative to L-lactate, and butyrate and valerate were the main products. CONCLUSION:The probiotic effect of fermented feed is associated with the modulation of lactate metabolism in the digestive organs of pigs. |
| 巻・号 | 135(10) |
| 公開日 | 2024-10-3 |
| DOI | 10.1093/jambio/lxae254 |
| PII | 7783268 |
| PMID | 39333026 |
| MeSH | Animal Feed* / analysis Animals Feces* / microbiology Fermentation* Gastrointestinal Microbiome* Lactic Acid* / metabolism Megasphaera elsdenii / metabolism Probiotics RNA, Ribosomal, 16S* / genetics Swine |
| リソース情報 | |
| 一般微生物 | JCM35777 JCM35778 JCM35779 |