論文 - 詳細
| RRC ID | 968 |
|---|---|
| 著者 | Hirose K, Hashimoto A, Tamura K, Kawamura Y, Ezaki T, Sagara H, Watanabe H. |
| タイトル | DNA sequence analysis of DNA gyrase and DNA topoisomerase IV quinolone resistance-determining regions of Salmonella enterica serovar Typhi and serovar Paratyphi A. |
| ジャーナル | Antimicrob Agents Chemother |
| Abstract |
The mutations that are responsible for fluoroquinolone resistance in the gyrA, gyrB, parC, and parE genes of Salmonella enterica serovar Typhi and serovar Paratyphi A were investigated. The sequences of the quinolone resistance-determining region of the gyrA gene in clinical isolates which showed decreased susceptibilities to fluoroquinolones had a single mutation at either the Ser-83 or the Asp-87 codon, and no mutations were found in the gyrB, parC, and parE genes. |
| 巻・号 | 46(10) |
| ページ | 3249-52 |
| 公開日 | 2002-10-1 |
| DOI | 10.1128/AAC.46.10.3249-3252.2002 |
| PMID | 12234852 |
| PMC | PMC128770 |
| MeSH | Anti-Infective Agents / pharmacology* DNA Gyrase / genetics* DNA Topoisomerase IV / genetics* Drug Resistance, Bacterial / genetics* Fluoroquinolones Microbial Sensitivity Tests Molecular Sequence Data Mutation Salmonella paratyphi A / drug effects* Salmonella paratyphi A / enzymology Salmonella paratyphi A / genetics Salmonella typhi / drug effects* Salmonella typhi / enzymology Salmonella typhi / genetics Sequence Analysis, DNA |
| IF | 4.904 |
| 引用数 | 74 |
| WOS 分野 | PHARMACOLOGY & PHARMACY MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Policy sources |
| 各媒体での言及数の合計 | 3 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 病原微生物 | |