| RRC ID |
971
|
| Author |
Akeda Y, Kodama T, Kashimoto T, Cantarelli V, Horiguchi Y, Nagayama K, Iida T, Honda T.
|
| Title |
Dominant-negative Rho, Rac, and Cdc42 facilitate the invasion process of Vibrio parahaemolyticus into Caco-2 cells.
|
| Journal |
Infect Immun
|
| Abstract |
To clarify the invasive process of Vibrio parahaemolyticus, an invasion assay was performed using cells expressing dominant negative small GTPases of the Rho family. This assay showed that the dominant negative host phenotype facilitates bacterial invasion, suggesting that the mechanism of V. parahaemolyticus invasion differs from that reported for other invasive bacteria.
|
| Volume |
70(2)
|
| Pages |
970-3
|
| Published |
2002-2-1
|
| DOI |
10.1128/IAI.70.2.970-973.2002
|
| PMID |
11796633
|
| PMC |
PMC127689
|
| MeSH |
Actins / metabolism
Caco-2 Cells
Humans
Vibrio parahaemolyticus / pathogenicity*
cdc42 GTP-Binding Protein / genetics
cdc42 GTP-Binding Protein / physiology*
rac1 GTP-Binding Protein / genetics
rac1 GTP-Binding Protein / physiology*
rhoA GTP-Binding Protein / genetics
rhoA GTP-Binding Protein / physiology*
|
| IF |
3.201
|
| Times Cited |
17
|
|
WOS Category
|
INFECTIOUS DISEASES
IMMUNOLOGY
|
| Resource |
| Pathogenic microorganisms |
V. parahaemolyticus? |
