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  • Search Condition : Filter (MeSH = cdc42 GTP-Binding Protein / genetics)
Species Resource Title
Zebrafish UAS:GFP Cdc42 mediates Bmp-induced sprouting angiogenesis through Fmnl3-driven assembly of endothelial filopodia in zebrafish.
Yeast The Cdc42 GAP Rga6 promotes monopolar outgrowth of spores.
Yeast Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Macrothrombocytopenia of Takenouchi-Kosaki syndrome is ameliorated by CDC42 specific- and lipidation inhibitors in MEG-01 cells.
Human and Animal Cells TE-1(RCB1894) , TE-8(RCB2098) Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma.
Human and Animal Cells HeLa(RCB0007) Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling.
C.elegans tm9602 Pathogenetic basis of Takenouchi-Kosaki syndrome: Electron microscopy study using platelets in patients and functional studies in a Caenorhabditis elegans model.
C.elegans tm3663 Mechanisms of CDC-42 activation during contact-induced cell polarization.
Human and Animal Cells HuH-7 A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Drosophila 2055R-1 , 2055R-2 Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia.
Drosophila 5462R-2 , 5462R-3 , UAS-JNK-RNAi The Cdc42/Par6/aPKC polarity complex regulates apoptosis-induced compensatory proliferation in epithelia.
Drosophila 2248R-2 Rho-family small GTPases are required for cell polarization and directional sensing in Drosophila wound healing.
Drosophila 12530R-2 The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release.
DNA material AxCANLacZ (RDB1749) Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells.
Human and Animal Cells WS3RGB(GMC0007) , WS6RGB(GMC0009) Defective cholesterol efflux in Werner syndrome fibroblasts and its phenotypic correction by Cdc42, a RhoGTPase.
Pathogenic microorganisms V. parahaemolyticus? Dominant-negative Rho, Rac, and Cdc42 facilitate the invasion process of Vibrio parahaemolyticus into Caco-2 cells.