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  • Search Condition : Filter (MeSH = Alzheimer Disease / genetics)
Species Resource Title
Drosophila Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies.
C.elegans tm6026 Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
Human and Animal Cells COS-7(RCB0539) TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
Human and Animal Cells 201B7(HPS0063) Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
Mice B6.129P2-Nfe2l2<tm1Mym>/MymRbrc(RBRC01390) Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
C.elegans tm385 Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans.
C.elegans tm1779 Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.
C.elegans tm2034 Toxic role of K+ channel oxidation in mammalian brain.
Human and Animal Cells Polyglutamine expansion mutation yields a pathological epitope linked to nucleation of protein aggregate: determinant of Huntington's disease onset.
Drosophila 7899R-2 , 8604R-1 , 8604R-2 , 3546R-1 , 8276R-2 , 8276R-3 , 1090R-1 , 1090R-2 , 10920R-2 , 10920R-3 , ... Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.
Zebrafish Tg(HuC:Kaede)/rw0130a Quantitative proteomics reveals diverse roles of miR-148a from gastric cancer progression to neurological development.
C.elegans tm465 , tm776 REST and stress resistance in ageing and Alzheimer's disease.
Drosophila NP6590 (DGRC#105275) Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein.
C.elegans Caenorhabditis elegans ptl-1(tm543) PTL-1 regulates neuronal integrity and lifespan in C. elegans.
Drosophila Alzheimer's disease: insights from Drosophila melanogaster models.
C.elegans ? Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors.
Drosophila Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease.