1. ホーム
  2. 一覧
論文 特許

論文 - 一覧

  • 23 Hits
  • 検索条件 : 絞込み (MeSH = Alzheimer Disease / genetics)
生物種 リソース名 タイトル
遺伝子材料 Alcadein a-FLAG /pcDNA3.1(+) (RDB19587) , Alcadein b-FLAG /pcDNA3.1(+) (RDB19588) , Alcadein g-FLAG /pcDNA3.1(+) (RDB19589) Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction.
実験動物マウス RBRC02370 Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Tau phosphorylation affects its axonal transport and degradation.
ヒト・動物細胞 PC-12(RCB0009) Neurite Outgrowth-Promoting Activity of Compounds in PC12 Cells from Sunflower Seeds.
実験動物マウス RBRC06334 Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
ショウジョウバエ Microtubule affinity-regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration.
ショウジョウバエ Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies.
線虫 tm6026 Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
ヒト・動物細胞 COS-7(RCB0539) TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
ヒト・動物細胞 201B7(HPS0063) Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
実験動物マウス RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
線虫 tm385 Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans.
線虫 tm1779 Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.
線虫 tm2034 Toxic role of K+ channel oxidation in mammalian brain.
ヒト・動物細胞 COS-7(RCB0539) Polyglutamine expansion mutation yields a pathological epitope linked to nucleation of protein aggregate: determinant of Huntington's disease onset.
ショウジョウバエ 7899R-2 , 8604R-1 , 8604R-2 , 3546R-1 , 8276R-2 , 8276R-3 , 1090R-1 , 1090R-2 , 10920R-2 , 10920R-3 , ... Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.
ゼブラフィッシュ Tg(HuC:Kaede)/rw0130a Quantitative proteomics reveals diverse roles of miR-148a from gastric cancer progression to neurological development.
線虫 tm465 , tm776 REST and stress resistance in ageing and Alzheimer's disease.
ショウジョウバエ NP6590 (DGRC#105275) Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein.
線虫 Caenorhabditis elegans ptl-1(tm543) PTL-1 regulates neuronal integrity and lifespan in C. elegans.