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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Alzheimer Disease / genetics)
生物種 リソース名 タイトル
実験動物マウス RBRC06344 The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research.
実験動物マウス RBRC06342 , RBRC06343 Sexual dimorphism, altered hippocampal glutamatergic neurotransmission, and cognitive impairment in APP knock-in mice.
ヒト・動物細胞 409B2(HPS0076) Enrichment of Allelic Editing Outcomes by Prime Editing in Induced Pluripotent Stem Cells.
実験動物マウス RBRC06343 Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging.
遺伝子材料 Alcadein a-FLAG /pcDNA3.1(+) (RDB19587) , Alcadein b-FLAG /pcDNA3.1(+) (RDB19588) , Alcadein g-FLAG /pcDNA3.1(+) (RDB19589) Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction.
実験動物マウス RBRC02370 Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Tau phosphorylation affects its axonal transport and degradation.
ヒト・動物細胞 PC-12(RCB0009) Neurite Outgrowth-Promoting Activity of Compounds in PC12 Cells from Sunflower Seeds.
実験動物マウス RBRC06334 Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
ショウジョウバエ Microtubule affinity-regulating kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration.
ショウジョウバエ Dysfunction of different cellular degradation pathways contributes to specific β-amyloid42-induced pathologies.
線虫 tm6026 Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
ヒト・動物細胞 COS-7(RCB0539) TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
ヒト・動物細胞 201B7(HPS0063) Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
実験動物マウス RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
線虫 tm385 Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans.
線虫 tm1779 Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.
線虫 tm2034 Toxic role of K+ channel oxidation in mammalian brain.
ヒト・動物細胞 COS-7(RCB0539) Polyglutamine expansion mutation yields a pathological epitope linked to nucleation of protein aggregate: determinant of Huntington's disease onset.
ショウジョウバエ 7899R-2 , 8604R-1 , 8604R-2 , 3546R-1 , 8276R-2 , 8276R-3 , 1090R-1 , 1090R-2 , 10920R-2 , 10920R-3 , ... Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.