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  • 検索条件 : 絞込み (MeSH = Alzheimer Disease / metabolism)
生物種 リソース名 タイトル
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Tau phosphorylation affects its axonal transport and degradation.
ヒト・動物細胞 MC3T3-G2/PA6(RCB1127) Optimized Ultrasonic Irradiation Finds Out Ultrastable Aβ1-40 Oligomers.
線虫 tm1264 , tm1312 , tm1182 , tm869 , tm1339 Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.
実験動物マウス RBRC06334 Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein.
実験動物マウス RBRC02192 Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.
実験動物マウス RBRC06334 AppNL-G-F/NL-G-F mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation.
ショウジョウバエ 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
線虫 tm6026 Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
線虫 tm385 Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans.
線虫 tm1961 , tm474 Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
ヒト・動物細胞 BM-MSCs Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes.
ヒト・動物細胞 anti-αB-crystallin(RCB1304) Specific association of small heat shock proteins with the pathological hallmarks of Alzheimer's disease brains.
ヒト・動物細胞 PC-12(RCB0009) Analysis of the secondary structure of beta-amyloid (Abeta42) fibrils by systematic proline replacement.
ヒト・動物細胞 PC-12(RCB0009) Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease.
ヒト・動物細胞 A pH-dependent conformational transition of Abeta peptide and physicochemical properties of the conformers in the glial cell.
ヒト・動物細胞 PC-12(RCB0009) Amyloid-β peptide increases cell surface localization of α7 ACh receptor to protect neurons from amyloid β-induced damage.
遺伝子材料 pGL4-phSESN2 (RDB07413) Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.
ゼブラフィッシュ Tg(HuC:Kaede)/rw0130a Quantitative proteomics reveals diverse roles of miR-148a from gastric cancer progression to neurological development.
遺伝子材料 W01A023B19 (HGE009243) , CSII-EF-RfA (RDB04387) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2.