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  • 検索条件 : 絞込み (MeSH = Alzheimer Disease / pathology)
生物種 リソース名 タイトル
ヒト・動物細胞 PC-12(RCB0009) Development of a brain-permeable peptide nanofiber that prevents aggregation of Alzheimer pathogenic proteins.
実験動物マウス RBRC02192 Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models.
線虫 tm1779 , tm376 Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
ショウジョウバエ DGRC#122076 Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
実験動物マウス RBRC06334 AppNL-G-F/NL-G-F mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation.
ショウジョウバエ 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
線虫 tm6026 Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
ヒト・動物細胞 293(RCB1637) Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
ヒト・動物細胞 201B7(HPS0063) Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
実験動物マウス RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
線虫 tm2034 Toxic role of K+ channel oxidation in mammalian brain.
ヒト・動物細胞 BM-MSCs Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes.
ヒト・動物細胞 KG-1-C(RCB0270) Eight-residue Abeta peptides inhibit the aggregation and enzymatic activity of Abeta42.
ヒト・動物細胞 PC-12(RCB0009) Amyloid-β peptide increases cell surface localization of α7 ACh receptor to protect neurons from amyloid β-induced damage.
遺伝子材料 W01A023B19 (HGE009243) , CSII-EF-RfA (RDB04387) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2.
線虫 tm465 , tm776 REST and stress resistance in ageing and Alzheimer's disease.
ショウジョウバエ 1009R-2 , 1009R-3 Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity.
線虫 Caenorhabditis elegans ptl-1(tm543) PTL-1 regulates neuronal integrity and lifespan in C. elegans.
実験動物マウス RBRC00806 Alzheimer disease-associated peptide, amyloid beta40, inhibits vascular regeneration with induction of endothelial autophagy.
ショウジョウバエ Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease.