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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Amyloid beta-Protein Precursor / genetics)
生物種 リソース名 タイトル
実験動物マウス RBRC03390 , RBRC03418 , RBRC06344 Apolipoprotein E genotype-dependent accumulation of amyloid β in APP-knock-in mouse model of Alzheimer's disease.
実験動物マウス RBRC06344 , RBRC03390 , RBRC03418 Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
ヒト・動物細胞 LoVo(RCB1639) Secretion of protease nexin-II/amyloid beta protein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors.
実験動物マウス RBRC02192 p38α-MAPK-deficient myeloid cells ameliorate symptoms and pathology of APP-transgenic Alzheimer's disease mice.
遺伝子材料 Alcadein a-FLAG /pcDNA3.1(+) (RDB19587) , Alcadein b-FLAG /pcDNA3.1(+) (RDB19588) , Alcadein g-FLAG /pcDNA3.1(+) (RDB19589) Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction.
実験動物マウス RBRC06344 14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer's Disease Mouse Models.
実験動物マウス , ヒト・動物細胞 RBRC06344 , MG6(RCB2403) Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.
実験動物マウス RBRC06334 Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
ヒト・動物細胞 MG6(RCB2403) An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.
実験動物マウス RBRC06334 AppNL-G-F/NL-G-F mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation.
ヒト・動物細胞 COS-7(RCB0539) TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
ヒト・動物細胞 201B7(HPS0063) Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
ヒト・動物細胞 MG6(RCB2403) Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice.
遺伝子材料 pTU1-PalphaAPP (RDB08714) O-Mannosylation is required for the solubilization of heterologously expressed human beta-amyloid precursor protein in Saccharomyces cerevisiae.
ショウジョウバエ FoxO mediates APP-induced AICD-dependent cell death.
線虫 tm2034 Toxic role of K+ channel oxidation in mammalian brain.
線虫 tm1961 , tm474 Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
ヒト・動物細胞 Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CSII-CMV-MCS (RDB04377). FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis.
ショウジョウバエ NP6590 (DGRC#105275) Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein.