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When you enter multiple keywords separated by space, your search will contain results that match any of the keywords (OR search).
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16 Hits
Search Condition : Filter (MeSH = Amyloid beta-Protein Precursor / genetics)
Species
Resource
RRC ID
Title
Journal
Published
Link
Human and Animal Cells
MG6(RCB2403)
58033
An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.
J Neuroinflammation
2019-8-30
Pubmed
Full text
Mice
C57BL/6-App
(RBRC06344)
57614
App
NL-G-F/NL-G-F
mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation.
Neurochem Int
2019-10-1
Pubmed
Full text
Human and Animal Cells
COS-7(RCB0539)
54051
TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
PLoS One
2018-8-7
Pubmed
Full text
Human and Animal Cells
201B7(HPS0063)
52671
Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
Nat Commun
2018-4-16
Pubmed
Full text
Human and Animal Cells
MG6(RCB2403)
48842
Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice.
Brain Behav Immun
2017-10-1
Pubmed
Full text
DNA material
pTU1-PalphaAPP (RDB08714)
48818
O-Mannosylation is required for the solubilization of heterologously expressed human beta-amyloid precursor protein in Saccharomyces cerevisiae.
Genes Cells
2009-2-1
Pubmed
Full text
Drosophila
47082
FoxO mediates APP-induced AICD-dependent cell death.
Cell Death Dis
2014-5-15
Pubmed
Full text
C.elegans
tm2034
46052
Toxic role of K+ channel oxidation in mammalian brain.
J Neurosci
2012-3-21
Pubmed
Full text
C.elegans
tm1961
,
tm474
46038
Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
Invert Neurosci
2011-12-1
Pubmed
Full text
Human and Animal Cells
44880
Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells.
Neurosci Lett
2013-12-17
Pubmed
DNA material
pCAG-HIVgp (RDB04394)
,
pCMV-VSV-G-RSV-Rev (RDB04393)
,
CSII-CMV-MCS (RDB04377).
34816
FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis.
J Neurosci
2012-3-7
Pubmed
Full text
Drosophila
NP6590 (DGRC#105275)
22042
Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein.
PLoS One
2013-2-7
Pubmed
Full text
Human and Animal Cells
Atg5^(+/+)MEF (RCB2710) Atg5^(-/-)MEF (RCB2711)
18201
A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
FASEB J
2011-6-1
Pubmed
Full text
C.elegans
?
6377
Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors.
Cell Mol Life Sci
2009-7-1
Pubmed
Full text
DNA material
pco12 EGFR (RDB01276)
4786
Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner.
J Neurosci
2001-3-15
Pubmed
DNA material
APP cDNA (AZ-10)
4784
Amyloid beta protein precursor is involved in the growth of human colon carcinoma cell in vitro and in vivo.
Int J Cancer
2001-4-1
Pubmed