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  • 16 Hits
  • Search Condition : Filter (MeSH = Amyloid beta-Protein Precursor / genetics)
Species Resource Title
Human and Animal Cells MG6(RCB2403) An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.
Mice C57BL/6-App(RBRC06344) AppNL-G-F/NL-G-F mice overall do not show impaired motivation, but cored amyloid plaques in the striatum are inversely correlated with motivation.
Human and Animal Cells COS-7(RCB0539) TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
Human and Animal Cells 201B7(HPS0063) Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.
Human and Animal Cells MG6(RCB2403) Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice.
DNA material pTU1-PalphaAPP (RDB08714) O-Mannosylation is required for the solubilization of heterologously expressed human beta-amyloid precursor protein in Saccharomyces cerevisiae.
Drosophila FoxO mediates APP-induced AICD-dependent cell death.
C.elegans tm2034 Toxic role of K+ channel oxidation in mammalian brain.
C.elegans tm1961 , tm474 Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
Human and Animal Cells Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CSII-CMV-MCS (RDB04377). FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis.
Drosophila NP6590 (DGRC#105275) Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein.
Human and Animal Cells Atg5^(+/+)MEF (RCB2710) Atg5^(-/-)MEF (RCB2711) A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
C.elegans ? Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors.
DNA material pco12 EGFR (RDB01276) Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner.
DNA material APP cDNA (AZ-10) Amyloid beta protein precursor is involved in the growth of human colon carcinoma cell in vitro and in vivo.