生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ゼブラフィッシュ
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Tg (hb9:Venus)
,
RIKEN WT
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66067
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Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations.
|
Stem Cell Reports |
2021-6-8 |
Pubmed
Full text
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ヒト・動物細胞
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CiRA00026(HPS0294)
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63110
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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
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Cell |
2020-10-29 |
Pubmed
Full text
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ゼブラフィッシュ
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Tg[UAS:mRFP1-TDP-43z]
,
Tg[UAS:mRFP1-CRY2olig]
,
Tg[UAS:opTDP-43z]
,
Tg[mnr2b-hs:EGFP-TDP-43z]
,
Tg[mnr2b-hs:opTDP-43h]
,
Tg[mnr2b-hs:opTDP-43hA315T]
|
60099
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Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons.
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Nat Commun |
2020-2-21 |
Pubmed
Full text
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ショウジョウバエ
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|
57236
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Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.
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Autophagy |
2017-9-18 |
Pubmed
Full text
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ショウジョウバエ
|
|
54544
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Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis.
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Mol Neurodegener |
2015-4-10 |
Pubmed
Full text
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遺伝子材料
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CMV:TDP43-GFP (RDB15742)
,
CMV:GFP-TDP25 (RDB15743)
,
CMV:GFP-NLS-TDP25 (RDB15744)
,
CMV:GFP-NLSNP-TDP25 (RDB15745)
,
GFP-NLS NP (RDB15746)
,
mCherry-Ubiquitin (RDB15747).
|
52780
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Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.
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Sci Rep |
2016-1-13 |
Pubmed
Full text
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遺伝子材料
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CMV:HSP70-mCherry (RDB15748).
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51311
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Different aggregation states of a nuclear localization signal-tagged 25-kDa C-terminal fragment of TAR RNA/DNA-binding protein 43 kDa.
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Genes Cells |
2017-6-1 |
Pubmed
Full text
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遺伝子材料
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pEF-BOS FLAG-mouse Rab29 (RDB14971)
,
pEF-BOS FLAG-mouse Rab29-Q67L (RDB14972)
,
pEF-BOS FLAG-mouse Rab29-T21N (RDB14973).
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48779
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C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
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Brain |
2017-4-1 |
Pubmed
Full text
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線虫
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tm1411
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45983
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VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans.
|
PLoS Genet |
2013-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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NB2a(RCB2639)
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38204
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DJ-1 forms complexes with mutant SOD1 and ameliorates its toxicity.
|
J Neurochem |
2010-5-1 |
Pubmed
Full text
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ヒト・動物細胞
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NB2a(RCB2639)
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17679
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Derlin-1 overexpression ameliorates mutant SOD1-induced endoplasmic reticulum stress by reducing mutant SOD1 accumulation.
|
Neurochem Int |
2011-2-1 |
Pubmed
Full text
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