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11 Hits
Search Condition : Filter (MeSH = Amyotrophic Lateral Sclerosis / metabolism*)
Species
Resource
RRC ID
Title
Journal
Published
Link
Zebrafish
Tg (hb9:Venus)
,
RIKEN WT
66067
Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations.
Stem Cell Reports
2021-6-8
Pubmed
Full text
Human and Animal Cells
CiRA00026(HPS0294)
63110
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
Cell
2020-10-29
Pubmed
Full text
Zebrafish
Tg[UAS:mRFP1-TDP-43z]
,
Tg[UAS:mRFP1-CRY2olig]
,
Tg[UAS:opTDP-43z]
,
Tg[mnr2b-hs:EGFP-TDP-43z]
,
Tg[mnr2b-hs:opTDP-43h]
,
Tg[mnr2b-hs:opTDP-43hA315T]
60099
Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons.
Nat Commun
2020-2-21
Pubmed
Full text
Drosophila
57236
Mask mitigates MAPT- and FUS-induced degeneration by enhancing autophagy through lysosomal acidification.
Autophagy
2017-9-18
Pubmed
Full text
Drosophila
54544
Calcium-responsive transactivator (CREST) protein shares a set of structural and functional traits with other proteins associated with amyotrophic lateral sclerosis.
Mol Neurodegener
2015-4-10
Pubmed
Full text
DNA material
CMV:TDP43-GFP (RDB15742)
,
CMV:GFP-TDP25 (RDB15743)
,
CMV:GFP-NLS-TDP25 (RDB15744)
,
CMV:GFP-NLSNP-TDP25 (RDB15745)
,
GFP-NLS NP (RDB15746)
,
mCherry-Ubiquitin (RDB15747).
52780
Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.
Sci Rep
2016-1-13
Pubmed
Full text
DNA material
CMV:HSP70-mCherry (RDB15748).
51311
Different aggregation states of a nuclear localization signal-tagged 25-kDa C-terminal fragment of TAR RNA/DNA-binding protein 43 kDa.
Genes Cells
2017-6-1
Pubmed
Full text
DNA material
pEF-BOS FLAG-mouse Rab29 (RDB14971)
,
pEF-BOS FLAG-mouse Rab29-Q67L (RDB14972)
,
pEF-BOS FLAG-mouse Rab29-T21N (RDB14973).
48779
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
Brain
2017-4-1
Pubmed
Full text
C.elegans
tm1411
45983
VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans.
PLoS Genet
2013-1-1
Pubmed
Full text
Human and Animal Cells
NB2a(RCB2639)
38204
DJ-1 forms complexes with mutant SOD1 and ameliorates its toxicity.
J Neurochem
2010-5-1
Pubmed
Full text
Human and Animal Cells
NB2a(RCB2639)
17679
Derlin-1 overexpression ameliorates mutant SOD1-induced endoplasmic reticulum stress by reducing mutant SOD1 accumulation.
Neurochem Int
2011-2-1
Pubmed
Full text