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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Amyotrophic Lateral Sclerosis / pathology)
生物種 リソース名 タイトル
線虫 tm4439 , tm985 TDP-43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models.
線虫 tm324 Neurons dispose of hyperactive kinesin into glial cells for clearance.
ヒト・動物細胞 HPS0097(HPS0097) , 454E2(HPS0077) Loss of intracellular ATP affects axoplasmic viscosity and pathological protein aggregation in mammalian neurons.
実験動物マウス RBRCGD000108 , RBRCGD000110 Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
ショウジョウバエ 11027R-2 , 11027R-3 , 30170R-1 , 30170R-2 , 4155R-1 , 4155R-2 , 9379R-2 , 9379R-3 , 9429R-1 , 9429R-2 , ... ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD.
ゼブラフィッシュ Multi-phaseted problems of TDP-43 in selective neuronal vulnerability in ALS.
ヒト・動物細胞 CiRA00026(HPS0294) TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
ゼブラフィッシュ Tg(hb9:Venus) Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
ゼブラフィッシュ Tg(HuC:GVP), UAS:GFP Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis.
線虫 tm776 Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
ショウジョウバエ Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.
ショウジョウバエ DGRC#108330 TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
線虫 tm776 A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model.
線虫 tm7084 The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival.
ショウジョウバエ Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration.
ショウジョウバエ RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
線虫 tm1 , tm4439 FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.
ゼブラフィッシュ pT2KXIGdeltaIN , SAGFF(LF)73A Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration.
ゼブラフィッシュ Tg(Huc:Kaede) ALS-linked protein disulfide isomerase variants cause motor dysfunction.
遺伝子材料 pEF-BOS FLAG-mouse Rab29 (RDB14971) , pEF-BOS FLAG-mouse Rab29-Q67L (RDB14972) , pEF-BOS FLAG-mouse Rab29-T21N (RDB14973). C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.