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  • 16 Hits
  • Search Condition : Filter (MeSH = Amyotrophic Lateral Sclerosis / pathology)
Species Resource
Zebrafish Tg(hb9:Venus) Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
Zebrafish Tg(HuC:GVP) Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis.
C.elegans Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
C.elegans tm776 A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model.
C.elegans tm7084 The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival.
Drosophila Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration.
Drosophila RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
C.elegans tm1 , tm4439 FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.
Zebrafish Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration.
Zebrafish Tg(Huc:Kaede) ALS-linked protein disulfide isomerase variants cause motor dysfunction.
DNA material pEF-BOS FLAG-mouse Rab29 (RDB14971) , pEF-BOS FLAG-mouse Rab29-Q67L (RDB14972) , pEF-BOS FLAG-mouse Rab29-T21N (RDB14973). C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
Drosophila 9553R-3 Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.
C.elegans tm1411 VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans.
Zebrafish Tg(isl1:GFP)/rw0 Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model.
Human and Animal Cells SK-N-SH (RCB0426) Familial amyotrophic lateral sclerosis (FALS)-linked SOD1 mutation accelerates neuronal cell death by activating cleavage of caspase-4 under ER stress in an in vitro model of FALS.
Human and Animal Cells GI-1 VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.