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  • Search Condition : Filter (MeSH = Carcinogenesis / genetics)
Species Resource Title
Human and Animal Cells NOS-1(RCB1032) Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma.
Human and Animal Cells PANC-1(RCB2095) Role of miR-30a-3p Regulation of Oncogenic Targets in Pancreatic Ductal Adenocarcinoma Pathogenesis.
DNA material pENTR4-H1 (RDB04395) , CSII-EF-RfA (RDB04387) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma-initiating cell properties via DNA methyltransferase 3A.
Human and Animal Cells ACC-MESO-1(RCB2292) Long Non-coding RNA LINC00152 Requires EZH2 to Promote Mesothelioma Cell Proliferation, Migration, and Invasion.
Human and Animal Cells Human dermal fibroblasts Promotion of squamous cell carcinoma tumorigenesis by oncogene-mediated THG-1/TSC22D4 phosphorylation.
Drosophila 9293Ra-2  Tctp, a unique Ing5-binding partner, inhibits the chromatin binding of Enok in Drosophila.
Human and Animal Cells HuH-7 ETV4 potentiates nuclear YAP retention and activities to enhance the progression of hepatocellular carcinoma.
Human and Animal Cells COLO-320(RCB1193) , Ba/F3(RCB0805) HER2 G776S mutation promotes oncogenic potential in colorectal cancer cells when accompanied by loss of APC function.
Human and Animal Cells Kato III(RCB2088) , MKN1(RCB1003) , MKN-7(RCB3687) , MKN45(RCB1001) MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target.
Human and Animal Cells MMAc(RCB0808) , MCF7(RCB1904) , Hep G2(RCB1648) , HCT116(RCB2979) , A549(RCB0098) , LNCap.FGC(RCB2144) , PANC-1(RCB2095) HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.
Drosophila Modeling Notch-Induced Tumor Cell Survival in the Drosophila Ovary Identifies Cellular and Transcriptional Response to Nuclear NICD Accumulation.
Zebrafish Tg(krt4p:gal4; UAS:EGFP) Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis.
Zebrafish , Human and Animal Cells Tg(6xTcf/LefBS-miniP:d2EGFP) , Cle-H3(RCB0549) A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.
Human and Animal Cells 293T(RCB2202) SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability.
Mice RBRC00107 An organoid-based carcinogenesis model induced by in vitro chemical treatment.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CS-RfA-CG (RDB04390) , pENTR4-H1 (RDB04395) 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
Human and Animal Cells SAS(RCB1974) Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer.
Human and Animal Cells HuH-7 Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1α and Epithelial-Mesenchymal Transition.
Human and Animal Cells MKN1(RCB1003) Profiling of Virus-Encoded MicroRNAs in Epstein-Barr Virus-Associated Gastric Carcinoma and Their Roles in Gastric Carcinogenesis.
Human and Animal Cells KGN(RCB1154) RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line.