生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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II-18(RCB2093)
,
PC-14(RCB0446)
,
RERF-LC-KJ(RCB1313)
|
71654
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Drug resistance to paclitaxel is not only associated with ABCB1 mRNA expression but also with drug accumulation in intracellular compartments in human lung cancer cell lines.
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Int J Oncol |
2012-4-1 |
Pubmed
Full text
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ヒト・動物細胞
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A549
,
PC-9(RCB4455)
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70118
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Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549cells.
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Biochem Biophys Res Commun |
2021-8-20 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3(RCB0805)
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69464
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Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS-MAPK Reactivation.
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Cancer Discov |
2021-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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EBC-1(RCB1965)
,
LK-2(RCB1970)
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68989
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Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma.
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Int J Cancer |
2014-8-15 |
Pubmed
Full text
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ヒト・動物細胞
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LC-2/ad(RCB0440)
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68852
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Bias-Corrected Targeted Next-Generation Sequencing for Rapid, Multiplexed Detection of Actionable Alterations in Cell-Free DNA from Advanced Lung Cancer Patients.
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Clin Cancer Res |
2016-2-15 |
Pubmed
Full text
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ヒト・動物細胞
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A549(RCB0098)
,
LC-2/ad(RCB0440)
,
RERF-LC-KJ(RCB1313)
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68848
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MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells.
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Mol Cancer Ther |
2014-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3
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68843
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Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib.
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Clin Cancer Res |
2014-11-15 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
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68842
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Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
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Cancer Sci |
2021-9-1 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
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68841
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Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer.
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Nat Commun |
2021-6-17 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
|
67813
|
Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase‑inhibitory fluoropyrimidine in EGFR‑mutated lung adenocarcinoma: retrospective and in vitro studies.
|
Int J Oncol |
2015-3-1 |
Pubmed
Full text
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ヒト・動物細胞
|
A549(RCB0098)
,
LC-2/ad(RCB0440)
|
67405
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Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.
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Mol Cancer Ther |
2015-11-1 |
Pubmed
Full text
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ヒト・動物細胞
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II-18(RCB2093)
|
67190
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A peptide antigen derived from EGFR T790M is immunogenic in non‑small cell lung cancer.
|
Int J Oncol |
2015-2-1 |
Pubmed
Full text
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ヒト・動物細胞
|
PC-9(RCB4455)
|
66852
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ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in EGFR-Mutated Non-Small Cell Lung Cancer.
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Clin Cancer Res |
2020-5-1 |
Pubmed
Full text
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ヒト・動物細胞
|
LK-2(RCB1970)
,
RERF-LC-AI(RCB0444)
,
EBC-1(RCB1965)
,
LC-1/sq-SF(RCB0438)
|
66847
|
Recruitment of KMT2C/MLL3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in Cancer.
|
Cancer Res |
2021-6-15 |
Pubmed
Full text
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ヒト・動物細胞
|
PC-9(RCB4455)
|
65538
|
A novel, rapid point-of-care test for lung cancer patients to detect epidermal growth factor receptor gene mutations by using real-time droplet-PCR and fresh liquid cytology specimens.
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Oncol Rep |
2017-2-1 |
Pubmed
Full text
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線虫
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tm2526
,
tm2518
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65299
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Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling.
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Int J Mol Sci |
2020-10-20 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
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65151
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Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer.
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Clin Cancer Res |
2019-2-15 |
Pubmed
Full text
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ヒト・動物細胞
|
PC-9(RCB4455)
|
65037
|
Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
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J Med Chem |
2017-4-13 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
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65019
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Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
|
J Med Chem |
2016-3-10 |
Pubmed
Full text
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ヒト・動物細胞
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PC-14(RCB0446)
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64100
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CAFET algorithm reveals Wnt/PCP signature in lung squamous cell carcinoma.
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PLoS One |
2011-1-1 |
Pubmed
Full text
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