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  • 25 Hits
  • Search Condition : Filter (MeSH = Cell Transformation, Neoplastic / genetics)
Species Resource
DNA material pCMX-N/RBP-J (R218H) (RDB03022) Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling.
DNA material pp53-Box RE-TK hRluc(F) (RDB05593) RNF43 interacts with NEDL1 and regulates p53-mediated transcription.
Mice B6.Cg-Tg(CAG-cre)CZ-MO2Osb (RBRC01828) CIZ1, a p21Cip1/Waf1-interacting protein, functions as a tumor suppressor in vivo.
DNA material pRx nZ ires Neo (RDB01699). Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.
C.elegans tm1231 LET-418/Mi2 and SPR-5/LSD1 cooperatively prevent somatic reprogramming of C. elegans germline stem cells.
DNA material CSII-CMV-RfA (RDB04386) , CSII-EF-RfA (RDB04387). A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.
Mice B6.Cg-Trp53<tm1Sia>/Rbrc(RBRC01361) The Transcriptional Landscape of p53 Signalling Pathway.
C.elegans tm1729 Cell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegans.
Mice STOCK Tg(Nanog-GFP , Puro)1Yam(RBRC02290) Role of Lefty in the anti tumor activity of human adult liver stem cells.
Drosophila 5993R-2 , 4005R-2 Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila.
Human and Animal Cells Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models.
Human and Animal Cells TE-10(RCB2099) miR-27 is associated with chemoresistance in esophageal cancer through transformation of normal fibroblasts to cancer-associated fibroblasts.
Human and Animal Cells Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models.
Human and Animal Cells Specific role of JNK in the maintenance of the tumor-initiating capacity of A549 human non-small cell lung cancer cells.
Human and Animal Cells TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells.
Human and Animal Cells Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer.
Human and Animal Cells Therapeutic approaches targeting midkine suppress tumor growth and lung metastasis in osteosarcoma.
Human and Animal Cells Targeting anticancer drug delivery to pancreatic cancer cells using a fucose-bound nanoparticle approach.
Human and Animal Cells Epigenetic silencing of HOPX promotes cancer progression in colorectal cancer.
Human and Animal Cells SV-3Y1-C6 , E1A-3Y1-1 , 3Y1-B clone 1-6 Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration.