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  • 検索条件 : 絞込み (MeSH = Cell Transformation, Neoplastic / genetics)
生物種 リソース名 タイトル
遺伝子材料 Genome Network Project (GNP) Human cDNA IRAK069P02 (HGX027962) Diamond-Blackfan anemia gene product RPS19 counteracts SET to maintain p53 transcriptional activity and tumor suppressor function.
実験動物マウス RBRC02975 Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model.
実験動物マウス RBRC01361 JAK2V617F+ myeloproliferative neoplasm clones evoke paracrine DNA damage to adjacent normal cells through secretion of lipocalin-2.
実験動物マウス RBRC01361 Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera.
ヒト・動物細胞 NIH3T3 The stem cell transcription factor ZFP296 transforms NIH3T3 cells and promotes anchorage-independent growth of cancer cells.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) SETDB1 Inhibits p53-Mediated Apoptosis and Is Required for Formation of Pancreatic Ductal Adenocarcinomas in Mice.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
実験動物マウス RBRC02759 Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation.
ヒト・動物細胞 MKN7(RCB0999) , MKN28(RCB1000) , MKN45(RCB1001) , MKN74(RCB1002) , GCIY(RCB0555) Distinct expression of CDX2 and GATA4/5, development-related genes, in human gastric cancer cell lines.
ヒト・動物細胞 ACC-MESO-1(RCB2292) Long Non-coding RNA LINC00152 Requires EZH2 to Promote Mesothelioma Cell Proliferation, Migration, and Invasion.
ヒト・動物細胞 HCT116(RCB2979) Molecular Pathogenesis of Colorectal Cancer: Impact of Oncogenic Targets Regulated by Tumor Suppressive miR-139-3p.
ヒト・動物細胞 293(RCB1637) Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex.
ヒト・動物細胞 Kato III(RCB2088) , MKN1(RCB1003) , MKN-7(RCB3687) , MKN45(RCB1001) MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target.
ヒト・動物細胞 PANC-1(RCB2095) Impact of Oncogenic Targets Controlled by Tumor-Suppressive miR-30a-5p in Pancreatic Ductal Adenocarcinoma.
ヒト・動物細胞 IMR-32(RCB1895) NeuroD1 promotes neuroblastoma cell growth by inducing the expression of ALK.
遺伝子材料 CSII-CMV-MCS-IRES2-Bsd (RDB04385) Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3.
ショウジョウバエ 5993R-2 , 1322R-1 , 1322R-2 , DGRC#109005 Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila.
ヒト・動物細胞 RERF-LC-AI(RCB0444) , RERF-LC-KJ(RCB1313) RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non-Small Cell Lung Carcinomas Sensitive to MEK Inhibition.
ヒト・動物細胞 293T(RCB2202) Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells.
ヒト・動物細胞 TE-1(RCB1894) , TE-4(RCB2097) , TE-6(RCB1950) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) , TE-15(RCB1951) UHRF1 regulates global DNA hypomethylation and is associated with poor prognosis in esophageal squamous cell carcinoma.