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  • Search Condition : Filter (MeSH = Checkpoint Kinase 2)
Species Resource Title
Yeast FY23931 , FY16386 , FY25693 Smc5/6 Complex Promotes Rad3ATR Checkpoint Signaling at the Perturbed Replication Fork through Sumoylation of the RecQ Helicase Rqh1.
Drosophila 10010Ab-1 Maelstrom coordinates microtubule organization during Drosophila oogenesis through interaction with components of the MTOC.
DNA material S. pombe ORFeome clone SpYFH27F12 (SPW090932) , SpYFH45G09 (SPW098153). Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint.
Human and Animal Cells HeLa(RCB0007) Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1.
Human and Animal Cells WI-38 Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53.
Yeast CD16-1, TP4-5A, TP4-1D, JZ670 The Mek1 phosphorylation cascade plays a role in meiotic recombination of Schizosaccharomyces pombe.
Yeast FY14069 Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast.
Yeast Involvement of fission yeast Clr6-HDAC in regulation of the checkpoint kinase Cds1.
Yeast FY13580 Cds1 controls the release of Cdc14-like phosphatase Flp1 from the nucleolus to drive full activation of the checkpoint response to replication stress in fission yeast.
Yeast FY7448 A homeodomain transcription factor regulates the DNA replication checkpoint in yeast.
Drosophila DGRC#109793 Anaphase DNA bridges induced by lack of RecQ5 in Drosophila syncytial embryos.
C.elegans tm853 Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1.
Zebrafish RIKEN WT (RW) , rw021 (Tg(ath5:GFP))? , rw255(piy)? Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53.
C.elegans tm853 The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans.
Yeast FY16530(MS203-2) , FY16531(MS202-11) , FY16532(MS111m13) , FY16533(MS105-22C) , FY16534(MS133-1) , FY16535(MS114-3) , FY16536(MS128-15) , FY16537(MS163-10) , FY16538(MS111-6) , FY16539(MS105-25C) etc. The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeast.