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  • Search Condition : Filter (MeSH = Down-Regulation / physiology)
Species Resource Title
Mice RBRC00806 Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia.
Drosophila DGRC#203535 Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function.
Human and Animal Cells U937 Etidronate down-regulates Toll-like receptor 2 ligand-induced chemokine production by inhibiting MyD88 expression and NF-κB activation.
Human and Animal Cells HuH-7 CXCL3 contributes to CD133(+) CSCs maintenance and forms a positive feedback regulation loop with CD133 in HCC via Erk1/2 phosphorylation.
Human and Animal Cells Hep G2(RCB1886) Down-regulation of hepatic CYP3A1 expression in a rat model of indomethacin-induced small intestinal ulcers.
Human and Animal Cells MKN28(RCB1000) , MKN45(RCB1001) Calcyclin-binding protein inhibits proliferation, tumorigenicity, and invasion of gastric cancer.
Human and Animal Cells MKN1(RCB1003) , MKN28(RCB1000) , MKN45(RCB1001) , MKN74(RCB1002) , HGC-27(RCB0500) , GCIY(RCB0555) Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation.
Drosophila Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
Human and Animal Cells HuH-28(RCB1943) Alpha-L-Fucosidase Serves as a Prognostic Indicator for Intrahepatic Cholangiocarcinoma and Inhibits Its Invasion Capacity.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Hypoxic stress upregulates Kir2.1 expression by a pathway including hypoxic-inducible factor-1α and dynamin2 in brain capillary endothelial cells.
Human and Animal Cells MRC-5(RCB0211) Clarithromycin attenuates IL-13-induced periostin production in human lung fibroblasts.
Drosophila 4063R-2 Ebi modulates wing growth by ubiquitin-dependent downregulation of Crumbs in Drosophila.
C.elegans tm1473 , tm2365 , tm1797 , tm2418 , tm0830 , tm1093 , tm1770 Regulation of behavioral plasticity by systemic temperature signaling in Caenorhabditis elegans.
Human and Animal Cells HL60(RCB0041) Dimethyl fumarate induces apoptosis of hematopoietic tumor cells via inhibition of NF-κB nuclear translocation and down-regulation of Bcl-xL and XIAP.
Human and Animal Cells COLO 679(RCB0989) Pathobiological properties of the ubiquitin ligase Nedd4L in melanoma.
Human and Animal Cells RAW 264(RCB0535) , ST2(RCB0224) High molecular weight hyaluronic acid regulates osteoclast formation by inhibiting receptor activator of NF-κB ligand through Rho kinase.
Human and Animal Cells DT40(RCB1464) , ΔBLM-DT40(RCB1811) , ΔWRN-DT40(RCB1812) 3EZ,20Ac-ingenol, a catalytic inhibitor of topoisomerases, downregulates p-Akt and induces DSBs and apoptosis of DT40 cells.
Human and Animal Cells HuH-7 miR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells.
Human and Animal Cells SSP-25(RCB1293) , RBE(RCB1292) , TKKK(RCB1907) , TGBC2TKBRCB1130) , TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) , 293(RCB1637) Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer.