• 63 Hits
  • 検索条件 : 絞込み (MeSH = Drug Resistance, Neoplasm / drug effects*)
生物種 リソース名 タイトル
ヒト・動物細胞 MIA Paca2(RCB2094) , LU65(RCB1967) Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
ヒト・動物細胞 EBC-1(RCB1965) PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity.
ヒト・動物細胞 MKN74(RCB1002) , Kato III(RCB2088) Enhancement of 5-fluorouracil-induced cytotoxicity by leucovorin in 5-fluorouracil-resistant gastric cancer cells with upregulated expression of thymidylate synthase.
ヒト・動物細胞 A549(RCB0098) Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells.
ヒト・動物細胞 PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
ヒト・動物細胞 PC-9(RCB4455) DDX3X induces primary EGFR-TKI resistance based on intratumor heterogeneity in lung cancer cells harboring EGFR-activating mutations.
ヒト・動物細胞 Ba/F3-CL1(RCB4474) Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides.
ヒト・動物細胞 A549(RCB0098) Lurasidone Sensitizes Cancer Cells to Osimertinib by Inducing Autophagy and Reduction of Survivin.
ヒト・動物細胞 MG-63(RCB1890) Ca2+ -activated K+ channel KCa 1.1 as a therapeutic target to overcome chemoresistance in three-dimensional sarcoma spheroid models.
ヒト・動物細胞 HuH-7(RCB1366) Nrf2 signaling promotes cancer stemness, migration, and expression of ABC transporter genes in sorafenib-resistant hepatocellular carcinoma cells.
ヒト・動物細胞 293T(RCB2202) Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase.
ヒト・動物細胞 SK-MEL-28(RCB1930) Treatment of vemurafenib-resistant SKMEL-28 melanoma cells with paclitaxel.
ヒト・動物細胞 COLO205(RCB2127) , COLO-320(RCB1193) , CW-2(RCB0778) , HCT116(RCB2979) Early response in phosphorylation of ribosomal protein S6 is associated with sensitivity to trametinib in colorectal cancer cells.
ヒト・動物細胞 StromaNKtert(RCB2350) The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma.
ヒト・動物細胞 JHOC-5(RCB1520) Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.
ヒト・動物細胞 MKN45(RCB1001) , MKN74(RCB1002) Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.
ヒト・動物細胞 A549(RCB0098) Olanzapine, an Atypical Antipsychotic, Inhibits Survivin Expression and Sensitizes Cancer Cells to Chemotherapeutic Agents.
ヒト・動物細胞 TSt-4(RCB2116) The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization.
ヒト・動物細胞 A549(RCB0098) Aripiprazole, an Antipsychotic and Partial Dopamine Agonist, Inhibits Cancer Stem Cells and Reverses Chemoresistance.
ヒト・動物細胞 PC-9(RCB4455) The impact of intermittent versus continuous exposure to EGFR tyrosine kinase inhibitor on selection of EGFR T790M-mutant drug-resistant clones in a lung cancer cell line carrying activating EGFR mutation.