論文 - 詳細
| RRC ID | 69767 |
|---|---|
| 著者 | Gozgit JM, Vasbinder MM, Abo RP, Kunii K, Kuplast-Barr KG, Gui B, Lu AZ, Molina JR, Minissale E, Swinger KK, Wigle TJ, Blackwell DJ, Majer CR, Ren Y, Niepel M, Varsamis ZA, Nayak SP, Bamberg E, Mo JR, Church WD, Mady ASA, Song J, Utley L, Rao PE, Mitchison TJ, Kuntz KW, Richon VM, Keilhack H. |
| タイトル | PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity. |
| ジャーナル | Cancer Cell |
| 巻・号 | 39(9) |
| ページ | 1214-1226.e10 |
| 公開日 | 2021-9-13 |
| DOI | 10.1016/j.ccell.2021.06.018 |
| PII | S1535-6108(21)00340-8 |
| PMID | 34375612 |
| MeSH | Adaptive Immunity / drug effects Animals Cell Line, Tumor Cell Proliferation / drug effects Cell Survival / drug effects Drug Resistance, Neoplasm / drug effects* HEK293 Cells HeLa Cells Humans Interferon Type I / metabolism* Mice Neoplasms / drug therapy* Neoplasms / genetics Neoplasms / metabolism Nucleoside Transport Proteins / genetics* Nucleoside Transport Proteins / metabolism* Signal Transduction / drug effects Small Molecule Libraries / administration & dosage* Small Molecule Libraries / pharmacology Tumor Escape / drug effects Xenograft Model Antitumor Assays |
| IF | 26.602 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 82 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 9.0 |
| リソース情報 | |
| ヒト・動物細胞 | EBC-1(RCB1965) |