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  • 68 Hits
  • Search Condition : Filter (MeSH = Drug Resistance, Neoplasm / genetics)
Species Resource Title
Human and Animal Cells JHOS-2(RCB1521) , JHOS-4(RCB1678) Circular RNA circPBX3 promotes cisplatin resistance of ovarian cancer cells via interacting with IGF2BP2 to stabilize ATP7A mRNA expression.
Human and Animal Cells Ba/F3(RCB0805) , WEHI-3(RCB0035) Foretinib can overcome common on-target resistance mutations after capmatinib/tepotinib treatment in NSCLCs with MET exon 14 skipping mutation.
Human and Animal Cells 8505C(RCB2103) , HTC/C3(RCB0452) , HOTHC(RCB0662) BRAF Inhibitors Induce Feedback Activation of RAS Pathway in Thyroid Cancer Cells.
Human and Animal Cells Ba/F3(RCB0805) Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
Human and Animal Cells MKN1(RCB1003) Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies-the role of HAS2, SHB and HBEGF.
Human and Animal Cells PC-9(RCB4455) Heterogeneity among tumors with acquired resistance to EGFR tyrosine kinase inhibitors harboring EGFR-T790M mutation in non-small cell lung cancer cells.
Human and Animal Cells A549(RCB0098) , LC-2/ad(RCB0440) , RERF-LC-KJ(RCB1313) MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells.
Human and Animal Cells PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
Human and Animal Cells Ba/F3(RCB4476) Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor.
Human and Animal Cells PC-9(RCB4455) Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity.
Human and Animal Cells Kato III(RCB2088) , MKN74(RCB1002) , NUGC-4(RCB1939) , GSS(RCB2277) , GCIY(RCB0555) , MKN45(RCB1001) A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines.
Human and Animal Cells HuH-7(RCB1366) Nrf2 signaling promotes cancer stemness, migration, and expression of ABC transporter genes in sorafenib-resistant hepatocellular carcinoma cells.
DNA material Venus/pCS2 (RDB15116) Subtype-specific collaborative transcription factor networks are promoted by OCT4 in the progression of prostate cancer.
Human and Animal Cells JHOC-5(RCB1520) Metabolic alterations caused by HNF1β expression in ovarian clear cell carcinoma contribute to cell survival.
Human and Animal Cells Ba/F3(RCB0805) , WEHI-3(RCB0035) EGFR Exon 18 Mutations in Lung Cancer: Molecular Predictors of Augmented Sensitivity to Afatinib or Neratinib as Compared with First- or Third-Generation TKIs.
Human and Animal Cells CW-2(RCB0778) Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.
Human and Animal Cells StromaNKtert(RCB2350) The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.
Human and Animal Cells JHOS-2(RCB1521) , JHOC-5(RCB1520) CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents.
Human and Animal Cells Ba/F3(RCB0805) TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.