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  • Search Condition : Filter (MeSH = Enzyme Activation / drug effects)
Species Resource Title
Human and Animal Cells HL60(RCB0041) Fusarenon-X induced apoptosis in HL-60 cells depends on caspase activation and cytochrome c release.
Human and Animal Cells MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Human and Animal Cells RBE(RCB1292) JNK inhibitor SP600125 enhances TGF-β-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner.
Human and Animal Cells KGN(RCB1154) Procaspase-Activating Compound-1 Synergizes with TRAIL to Induce Apoptosis in Established Granulosa Cell Tumor Cell Line (KGN) and Explanted Patient Granulosa Cell Tumor Cells In Vitro.
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells PC-12(RCB0009) Midkine inhibits apoptosis via extracellular signal regulated kinase (ERK) activation in PC12 cells.
Human and Animal Cells MOLT-4(RCB0206) 2-Chloro-2'-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4.
Human and Animal Cells A549(RCB0098) Green tea polyphenol blocks h(2)o(2)-induced interleukin-8 production from human alveolar epithelial cells.
Human and Animal Cells NUGC-4(RCB1939) The novel VEGF receptor/MET-targeted kinase inhibitor TAS-115 has marked in vivo antitumor properties and a favorable tolerability profile.
Human and Animal Cells iPSC line Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells.
Human and Animal Cells WI-38(RCB0702) Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta1.
Human and Animal Cells RAW 264(RCB0535) Spred-2 deficiency exacerbates lipopolysaccharide-induced acute lung inflammation in mice.
Human and Animal Cells RGM1(RCB0876) ZINC40099027 Promotes Gastric Mucosal Repair in Ongoing Aspirin-Associated Gastric Injury by Activating Focal Adhesion Kinase.
Zebrafish RIKEN WT Clotrimazole inhibits the Wnt/β-catenin pathway by activating two eIF2α kinases: The heme-regulated translational inhibitor and the double-stranded RNA-induced protein kinase.
Human and Animal Cells StromaNKtert(RCB2350) Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells.
Human and Animal Cells RAW 264(RCB0535) Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways.
Human and Animal Cells B16 melanoma 4A5(RCB0557) Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity.
Human and Animal Cells ATDC5(RCB0565) Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes.
Human and Animal Cells PANC-1(RCB2095) 3EZ, 20Ac-ingenol-induced Apoptosis in Chemoresistant Cancers With Cyclin D1 Accumulation.
Human and Animal Cells C2C12(RCB0987) Alpha Mangostin promotes myogenic differentiation of C2C12 mouse myoblast cells.