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  • Search Condition : Filter (MeSH = ErbB Receptors / genetics)
Species Resource Title
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (REB04394) CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.
Human and Animal Cells YSCCC(RCB1549) , HuCCT1(RCB1960) , RBE(RCB1292) , SSP-25(RCB1292) Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors.
Human and Animal Cells RBE(RCB1292) EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma.
Human and Animal Cells CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
Human and Animal Cells MCF7(RCB1904) Suppression of heregulin β signaling by the single N-glycan deletion mutant of soluble ErbB3 protein.
Human and Animal Cells PC-14(RCB0446) High-fat diet induces C-reactive protein secretion, promoting lung adenocarcinoma via immune microenvironment modulation.
C.elegans tm810 Discovery of nonautonomous modulators of activated Ras.
Drosophila 1395R-1 , 4217R-2 EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation.
Drosophila DGRC#104055 Sas-Ptp10D shapes germ-line stem cell niche by facilitating JNK-mediated apoptosis.
Human and Animal Cells PC-9(RCB4455) Inhibition of EGFR and MEK surmounts entrectinib resistance in a brain metastasis model of NTRK1-rearranged tumor cells.
Human and Animal Cells PC-9(RCB4455) Osimertinib-tolerant lung cancer cells are susceptible to ferroptosis.
Human and Animal Cells II-18(RCB2093) Mutant forms of EGFR promote HER2 trafficking through efficient formation of HER2-EGFR heterodimers.
Human and Animal Cells PC-9(RCB4455) , Jurkat(RCB3052) A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations.
Drosophila EGFRAP encodes a new negative regulator of the EGFR acting in both normal and oncogenic EGFR/Ras-driven tissue morphogenesis.
Human and Animal Cells TE-1(RCB1894) , TE-9(RCB1988) , TE-11(RCB2100) Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling.
Human and Animal Cells HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , SAS(RCB1974) Epidermal growth factor/epidermal growth factor receptor signaling blockage inhibits tumor cell-derived exosome uptake by oral squamous cell carcinoma through macropinocytosis.
Human and Animal Cells PC-9(RCB4455) Design, synthesis and evaluation of the osimertinib analogue (C-005) as potent EGFR inhibitor against NSCLC.
Human and Animal Cells PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
Human and Animal Cells PC-9(RCB4455) Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer.
Human and Animal Cells PC-9(RCB4455) EphB4 as a Novel Target for the EGFR-Independent Suppressive Effects of Osimertinib on Cell Cycle Progression in Non-Small Cell Lung Cancer.