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Mice RBRC04790 Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis.
Human and Animal Cells PANC-1(RCB20265) , PK-59(RCB1901) , PK‐8(RCB2700) , MIA Paca2(RCB2094) Tumor microenvironmental 15-PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer.
Mice RBRC01939 Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas.
Mice RBRC02298 Fibrosis-memory is mediated by IL-3-producing T cells and drives progression of fibrosis.
Mice RBRC02759 Autophagy gene Atg7 regulates the development of radiation-induced skin injury and fibrosis of skin.
Mice RBRC03733 Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation.
Mice RBRC02759 Autophagy inhibition blunts PDGFRA adipose progenitors' cell-autonomous fibrogenic response to high-fat diet.
Human and Animal Cells 1231A3(HPS0381) iPSC-based drug discovery identified the Hippo signaling pathway as a therapeutic target in the fibrosis of NPHP1-deficient nephronophthisis.
Zebrafish UAS:GFP flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response.
Human and Animal Cells 293(RCB1637) , A549(RCB0098) Toxicological effects of Sb(III), Sb(V), and NMG-Sb(V) in human lung, kidney, and liver cells: cytotoxicity and fibrotic factor induction.
Human and Animal Cells Hep G2 Transforming Growth Factorβ1 Overexpression Is Associated with Insulin Resistance and Rapidly Progressive Kidney Fibrosis under Diabetic Conditions.
Mice RBRC05691 Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis.
Human and Animal Cells 1383D2(HPS1005) Subpopulations of fibroblasts derived from human iPS cells.
DNA material pCMFlag_hsSMAD3 (RDB07019) Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis.
Human and Animal Cells RAW 264(RCB0535) , C2C12(RCB0987) , NIH/3T3(RCB2767) Releasable, Immune-Instructive, Bioinspired Multilayer Coating Resists Implant-Induced Fibrosis while Accelerating Tissue Repair.
Human and Animal Cells RAW 264(RCB0535) Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice.
Human and Animal Cells HCE-T(RCB2280) Mesenchymal Stem Cell Exosomes as Immunomodulatory Therapy for Corneal Scarring.
Human and Animal Cells GCIY(RCB0555) , MKN-7(RCB3687) Candidate Oncogenes, ARHGAP4, NOS3, and OR51B5, for the Development of Scirrhous-type Gastric Cancer.
Human and Animal Cells PANC-1(RCB2095) ERAP2 is a novel target involved in autophagy and activation of pancreatic stellate cells via UPR signaling pathway.