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  • Search Condition : Filter (MeSH = GTPase-Activating Proteins / metabolism)
Species Resource Title
C.elegans tm2241 Endosomal trafficking protein TBC-2 modulates stress resistance and lifespan through DAF-16-dependent and independent mechanisms.
Human and Animal Cells MKN28(RCB1000) , MKN45(RCB1001) Helicobacter pylori-induced RASAL2 Through Activation of Nuclear Factor-κB Promotes Gastric Tumorigenesis via β-catenin Signaling Axis.
Yeast The Cdc42 GAP Rga6 promotes monopolar outgrowth of spores.
Human and Animal Cells M4(RCB1611) Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues.
Human and Animal Cells C2C12(RCB0987) Loss of HIF-1α impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells.
Human and Animal Cells Lu99(RCB1900) , PC-9(RCB4455) Engagement of overexpressed Her2 with GEP100 induces autonomous invasive activities and provides a biomarker for metastases of lung adenocarcinoma.
Zebrafish vglut2:dsRed , SAIGFF213A Two knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis.
Human and Animal Cells MC3T3-E1(RCB1126) Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner.
Yeast BYP1419 Pop2 phosphorylation at S39 contributes to the glucose repression of stress response genes, HSP12 and HSP26.
Drosophila Control of basal autophagy rate by vacuolar peduncle.
C.elegans tm1447 , tm2523 , tm2616 LET-413/Erbin acts as a RAB-5 effector to promote RAB-10 activation during endocytic recycling.
C.elegans tm1425 Cdc42 regulates junctional actin but not cell polarization in the Caenorhabditis elegans epidermis.
DNA material pEF-HA-mouse MICAL-L1 (RDB15385) , pEF-Myc-mouse EHD1 (RDB15386). Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth.
DNA material pEF-T7-human TBC1D12-N (RDB14979) , pEF-T7-human TBC1D12-M (RDB14980) , pEF-T7-human TBC1D12-TBC (RDB14981) , pEGFP-C1-human TBC1D12-R559K (RDB14999) , pEGFP-C1-human TBC1D28 (RDB15015) , pEGFP-C1-human TBC1D29 (RDB15016) , pGEX-4T-3-mouse Rab11A-Q70L (RDB15028) , pGEX-4T-3-mouse Rab11A-S25N (RDB15029) , pmStr-C1-mouse Rab11A (RDB15030) , pmStr-C1-mouse Rab11A-Q70L (RDB15031) , ... TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells.
DNA material pEGFP-C1-Rab40 (RDB14338) , pEF-BOS FLAG-mouse Rab2B (RDB14676) , pGEX-4T-3-mouse Rab29 (RDB14977) , pEGFP-C1-human TBC1D18 (RDB15005) , pGEX-4T-3-mouse Rab11A (RDB15027) , pGEX-4T-3-Rab1A (RDB16827) , pGEX-4T-3-Rab2A (RDB16828) , pGEX-4T-3-Rab3A (RDB16829) , pGEX-4T-3-Rab4A (RDB16830) , pGEX-4T-3-Rab5A (RDB16831) , ... Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.
C.elegans tm2328 , tm1447 The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions.
C.elegans tm1956 , tm1877 , tm3124 , tm1447 Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans.
C.elegans tm2616 , tm1909 Dynamic Opposition of Clustered Proteins Stabilizes Cortical Polarity in the C. elegans Zygote.
C.elegans tm2241 , tm1060 Basolateral Endocytic Recycling Requires RAB-10 and AMPH-1 Mediated Recruitment of RAB-5 GAP TBC-2 to Endosomes.
Rice Oryzabase Comparative and evolutionary analysis of genes encoding small GTPases and their activating proteins in eukaryotic genomes.