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  • 検索条件 : 絞込み (MeSH = Histones / metabolism)
生物種 リソース名 タイトル
ヒト・動物細胞 A549(RCB0098) Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break.
ヒト・動物細胞 MSCs Regulation of osteogenesis in bone marrow-derived mesenchymal stem cells via histone deacetylase 1 and 2 co-cultured with human gingival fibroblasts and periodontal ligament cells.
ヒト・動物細胞 ATN-1(RCB1440) , TL-Mor(RCB1881) Dual targeting of aberrant DNA and histone methylation synergistically suppresses tumor cell growth in ATL.
ショウジョウバエ 31617R-3 , 31617R-2 Chromatin state transitions in the Drosophila intestinal lineage identify principles of cell-type specification.
ヒト・動物細胞 MOLT-4(RCB0206) , SKW-3(RCB1168) Drug resistance to nelarabine in leukemia cell lines might be caused by reduced expression of deoxycytidine kinase through epigenetic mechanisms.
ヒト・動物細胞 HHUA(RCB0658) Anticancer activity of MS-275, a novel histone deacetylase inhibitor, against human endometrial cancer cells.
ヒト・動物細胞 BeWo(RCB1644) Histone deacetylase inhibitors induce growth inhibition, cell cycle arrest and apoptosis in human choriocarcinoma cells.
ヒト・動物細胞 OS-RC-2(RCB0735) Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
線虫 tm3858 Genetic analysis of Caenorhabditis elegans Haspin-like genes shows that hasp-1 plays multiple roles in the germline.
線虫 tm1489 , tm1624 , tm3746 , tm1818 , tm2963 , tm760 H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans.
線虫 tm3735 , tm2828 , tm2966 , tm3121 , tm3197 , tm1200 , tm3118 Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality.
線虫 tm872 , tm1301 Dual roles for piRNAs in promoting and preventing gene silencing in C. elegans.
線虫 tm6157 , tm1227 A chromodomain protein mediates heterochromatin-directed piRNA expression.
線虫 tm6845 , tm6748 , tm2649 , tm1116 SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity.
線虫 tm6369 Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans.
実験動物マウス RBRC05555 The EZH2-PRC2-H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasion.
ヒト・動物細胞 iPS-MEF-Fb/Ng-440A-3(APS0003) HDAC8 is implicated in embryoid body formation via canonical Hedgehog signaling and regulates neuronal differentiation.
ヒト・動物細胞 HuH-7 Adenosine N6-methylation upregulates the expression of human CYP2B6 by altering the chromatin status.
酵母 FY29134 The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric heterochromatin at the chromatin boundary.
酵母 Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors.