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  • Search Condition : Filter (MeSH = Hypoxia-Inducible Factor 1, alpha Subunit / genetics)
Species Resource Title
Human and Animal Cells Hep G2 Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1alpha-independent manner.
Human and Animal Cells A549 γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis.
Human and Animal Cells MC3T3-E1(RCB1126) HIF-1α plays an essential role in BMP9-mediated osteoblast differentiation through the induction of a glycolytic enzyme, PDK1.
Human and Animal Cells Saos-2(RCB0428) Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor HIF-1α in a p53-independent manner.
Human and Animal Cells COLO-320(RCB1193) HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) Matrix metalloproteinase‑1 expression is regulated by HIF‑1‑dependent and epigenetic mechanisms and serves a tumor‑suppressive role in gastric cancer progression.
Human and Animal Cells MH7A(RCB1512) Sustained Hypoxia Suppresses Joint Destruction in a Rat Model of Rheumatoid Arthritis via Negative Feedback of Hypoxia Inducible Factor-1α.
Human and Animal Cells MCF7(RCB1904) Hypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cells.
Human and Animal Cells B16F1(RCB2649) , B16F10(RCB2630) , B16F10/mGM(RCB1158) Acceleration of tumor growth due to dysfunction in M1 macrophages and enhanced angiogenesis in an animal model of autoimmune disease.
Human and Animal Cells WI-38(RCB0702) Antifibrotic effects of cyclosporine A on TGF-β1-treated lung fibroblasts and lungs from bleomycin-treated mice: role of hypoxia-inducible factor-1α.
Human and Animal Cells JHOC-7(RCB1688) , JHOC-9(RCB2226) MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.
General Microbes JCM1255 Analysis of hypoxia-associated dendritic cells in colitic mice and effects of probiotics on IL-10 production in inflammatory dendritic-cells under hypoxia.
Human and Animal Cells HuH-7 HIF-1α-induced RIT1 promotes liver cancer growth and metastasis and its deficiency increases sensitivity to sorafenib.
Mice RBRC01361 Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
Mice RBRC04874 HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment.
Human and Animal Cells HS-Sch-2(RCB2230) Hypoxia-inducible factor 1 alpha is a poor prognostic factor and potential therapeutic target in malignant peripheral nerve sheath tumor.
Human and Animal Cells MH7A(RCB1512) Synovial cell death is regulated by TNF-α-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1α.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Requirement of Hsp105 in CoCl2-induced HIF-1α accumulation and transcriptional activation.
Prokaryotes E. coli Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma.
DNA material AxCANCre (RDB01748) Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling.