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  • Search Condition : Filter (MeSH = Intracellular Signaling Peptides and Proteins / antagonists & inhibitors)
Species Resource Title
Human and Animal Cells G-415(RCB2640) Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma.
Human and Animal Cells DT40(RCB1464) Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
Human and Animal Cells HCE-T(RCB2280) MK2 inhibitor reduces alkali burn-induced inflammation in rat cornea.
Human and Animal Cells A549(RCB0098) Logical design of an anti-cancer agent targeting the plant homeodomain in Pygopus2.
DNA material pEF-T7-HPS4 (RDB17366) , pEF-T7-GST-RBD32/38 (RDB17371) RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes.
Human and Animal Cells HuCCT1(RCB1960) , TFK-1(RCB2537) Jab1 Silencing Inhibits Proliferation and Sensitizes to Cisplatin in Biliary Tract Cancer.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis.
Human and Animal Cells MIA Paca2(RCB2094) , PANC-1(RCB2095) Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
Drosophila 15161R-1 , 6129R-1 Components of Intraflagellar Transport Complex A Function Independently of the Cilium to Regulate Canonical Wnt Signaling in Drosophila.
Human and Animal Cells MC3T3-E1(RCB1126) , ST2(RCB0224) Spleen tyrosine kinase suppresses osteoblastic differentiation through MAPK and PKCα.