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Species Resource Title
DNA material pGFP-C220 (RDB20681) , pGFP-C233 (RDB20682) , pGFP-C243 (RDB20683) , pGFP-C253 (RDB20684) , pGFP-C263 (RDB20685) , pGFP-C274 (RDB20686) , pGFP-F220 (RDB20687) , pGFP-RRM2 (RDB20688) , pRFP-C220 (RDB20689) , pGFP-C220Δ (RDB20690) , ... Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity.
C.elegans tm1296 , tm892 , tm894 , tm3169 , tm2645 , tm3315 , tm2223 , tm1724 , tm1357 , tm2428 , ... Germ granule compartments coordinate specialized small RNA production.
C.elegans tm6845 , tm6748 , tm2649 , tm1116 SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity.
C.elegans The intrinsically disordered protein SPE-18 promotes localized assembly of MSP in Caenorhabditis elegans spermatocytes.
Zebrafish Tg[UAS:mRFP1-TDP-43z] , Tg[UAS:mRFP1-CRY2olig] , Tg[UAS:opTDP-43z] , Tg[mnr2b-hs:EGFP-TDP-43z] , Tg[mnr2b-hs:opTDP-43h] , Tg[mnr2b-hs:opTDP-43hA315T] Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons.
Drosophila DEAD-box RNA helicase Belle posttranscriptionally promotes gene expression in an ATPase activity-dependent manner.
C.elegans tm4844 , tm5004 , tm2252 , tm1358 , tm1301 Distinct regions of the intrinsically disordered protein MUT-16 mediate assembly of a small RNA amplification complex and promote phase separation of Mutator foci.