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  • 9 Hits
  • Search Condition : Filter (MeSH = Janus Kinase 2 / genetics)
Species Resource Title
Human and Animal Cells HUDEP-2(RCB4557) Genome editing to model and reverse a prevalent mutation associated with myeloproliferative neoplasms.
Human and Animal Cells StromaNKtert(RCB2350) Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor.
Human and Animal Cells MIA Paca2(RCB2094) The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines.
Human and Animal Cells MKN45(RCB1001) Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis.
Pathogenic microorganisms ? Miliary tuberculosis associated with chronic neutrophilic leukemia.
Human and Animal Cells F-36P(RCB0775) Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase.
Human and Animal Cells K562 Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
Human and Animal Cells Hep G2 Crosstalk of humoral and cell-cell contact-mediated signals in postnatal body growth.
DNA material pRx nZ ires Neo (RDB01699). Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.