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  • Search Condition : Filter (MeSH = Jumonji Domain-Containing Histone Demethylases / metabolism)
Species Resource Title
C.elegans tm3735 , tm2828 , tm2966 , tm3121 , tm3197 , tm1200 , tm3118 Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality.
Human and Animal Cells Lu-165(RCB1184) SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.
C.elegans tm5007 , tm3121 , tm3197 , tm3118 H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner.
Mice RBRC01834 UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes.
Human and Animal Cells ST2(RCB0224) Histone demethylase KDM7A reciprocally regulates adipogenic and osteogenic differentiation via regulation of C/EBPα and canonical Wnt signalling.
C.elegans tm1812 Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase.
C.elegans tm3735 JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity.
C.elegans tm3136 and tm3118 The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity.
C.elegans Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans.