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Species Resource Title
Drosophila Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
C.elegans tm1524 , tm1842 , tm1145 COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining.
Human and Animal Cells NIH3T3 , HeLa Nuclear localization of mouse Ku70 in interphase cells and focus formation of mouse Ku70 at DNA damage sites immediately after irradiation.
Human and Animal Cells MKN45(RCB1001) , COS-7(RCB0539) Runx3 interacts with DNA repair protein Ku70.
Human and Animal Cells 293(RCB1637) Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling.
Human and Animal Cells RERF-LC-AI(RCB0444) Suppression of a DNA double-strand break repair gene, Ku70, increases radio- and chemosensitivity in a human lung carcinoma cell line.
Drosophila Sterility of Drosophila with mutations in the Bloom syndrome gene--complementation by Ku70.
Yeast Hyperactive Cdc2 kinase interferes with the response to broken replication forks by trapping S.pombe Crb2 in its mitotic T215 phosphorylated state.
Drosophila DGRC#202656 Drosophila UTX coordinates with p53 to regulate ku80 expression in response to DNA damage.
DNA material AxCANCre (RDB01748) Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.