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  • Search Condition : Filter (MeSH = Lysosomes / genetics)
Species Resource Title
Mice RBRC00806 TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy.
C.elegans tm4481 ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress.
C.elegans tm1108 , tm1978 Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism.
Human and Animal Cells MG6(RCB2403) Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Human and Animal Cells 293T(RCB2202) Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain.
Drosophila Genetic screening of the genes interacting with Drosophila FIG4 identified a novel link between CMT-causing gene and long noncoding RNAs.
Human and Animal Cells PC-3(RCB2145) Galectin-9 induces atypical ubiquitination leading to cell death in PC-3 prostate cancer cells.
DNA material pMRX-puro-EGFP-Rab7 (RDB15975). Rab7 knockout unveils regulated autolysosome maturation induced by glutamine starvation.
Drosophila 1765R-2 , 1765R-4 Dpp regulates autophagy-dependent midgut removal and signals to block ecdysone production.
C.elegans tm327 , tm4103 , tm2608 , tm4137 , tm2241 Distinct roles of the two VPS33 proteins in the endolysosomal system in Caenorhabditis elegans.
DNA material pcDNA5-GAPDH-HaloTag (RDB15088) Fluorescent-based evaluation of chaperone-mediated autophagy and microautophagy activities in cultured cells.
C.elegans tm703 , tm830 , tm333 , tm688 A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function.
C.elegans tm2078 , tm2095 Residual body removal during spermatogenesis in C. elegans requires genes that mediate cell corpse clearance.
C.elegans tm1978 TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
C.elegans tm4475 PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation.
C.elegans tm3767 , tm1693 , tm1877 , tm1447 An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction.
Mice RBRC00806 RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4.
Drosophila Windpipe controls Drosophila intestinal homeostasis by regulating JAK/STAT pathway via promoting receptor endocytosis and lysosomal degradation.