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論文 - 一覧

  • 82 Hits
  • 検索条件 : 絞込み (MeSH = Lysosomes / metabolism*)
生物種 リソース名 タイトル
実験動物マウス RBRC00806 Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.
ヒト・動物細胞 HT1080(RCB1956) A polylysine-polyhistidine fusion peptide for lysosome-targeted protein delivery.
実験動物マウス RBRC00806 TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium.
実験動物マウス RBRC02975 Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
ヒト・動物細胞 THP-1(RCB1189) The lysosome rupture-activated TAK1-JNK pathway regulates NLRP3 inflammasome activation.
線虫 tm3425 Saturated very long chain fatty acid configures glycosphingolipid for lysosome homeostasis in long-lived C. elegans.
遺伝子材料 pMRX-IP-GFP-STX17 (RDB19636) , pMRX-IP-GFP-SNAP29 (RDB19638) , pMRX-IP-GFP-VAMP7 (RDB19639) , pMRX-IP-GFP-VAMP8 (RDB19640) , p3xFLAG-CMV10-Stx17 (RDB19761) , p3xFLAG-CMV10-SNAP29 (RDB19765) , p3xFLAG-CMV10-VAMP7 (RDB19778) , pMRXIP GFP-Stx7 (RDB19779) , pMRXIP-GFP-Stx18 (RDB19792) , pMRXIP-GFP-Stx17TM (RDB19793) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
ゼブラフィッシュ Tg(vglut2a:loxP-DsRed-loxP-GFP) G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
ヒト・動物細胞 201B7(HPS0063) Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease.
遺伝子材料 pMRX-puro-FLAG-hVPS52 (RDB18998) , pMRX-puro-FLAG-hVPS52_N670 (RDB18999) , pMRX-puro-FLAG-hVPS52_N556 (RDB19000) , pMRX-puro-FLAG-hVPS52_N410 (RDB19001) , pMRX-bsr-ss-sfGFP (RDB19002) Knockout analysis of Rab6 effector proteins revealed the role of VPS52 in the secretory pathway.
ヒト・動物細胞 KP4(RCB1005) , PK-1(RCB1972) Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.
線虫 tm1108 , tm1978 Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) , RAW 264(RCB0535) Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.
ヒト・動物細胞 HuH-7(RCB1366) , CHO-K1(RCB0285) Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1.
ヒト・動物細胞 IMR-90-SV(RCB1024) , Rat-1(RCB1830) Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy.
遺伝子材料 pMRX-IP TFEB-sfGFP (RDB18607) , pCW DNAseIIα-sfGFP-T2A-mCherry (RDB18608) Identification of a factor controlling lysosomal homeostasis using a novel lysosomal trafficking probe.
ヒト・動物細胞 Atg5^(-/-)MEF(RCB2711) Sucrose induces vesicle accumulation and autophagy.
ヒト・動物細胞 ST2(RCB0224) Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis.
ショウジョウバエ 5520R-1 , 18255R-1 , 31014R-2 , 9726R-1 , 31015R-1 Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.