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  • 43 Hits
  • Search Condition : Filter (MeSH = MAP Kinase Signaling System / drug effects*)
Species Resource Title
Human and Animal Cells PC-12(RCB0009) Midkine inhibits apoptosis via extracellular signal regulated kinase (ERK) activation in PC12 cells.
Zebrafish Tg(6xTcf/LefBS-miniP:d2EGFP)isi01 Attenuating the Epidermal Growth Factor Receptor-Extracellular Signal-Regulated Kinase-Sex-Determining Region Y-Box 9 Axis Promotes Liver Progenitor Cell-Mediated Liver Regeneration in Zebrafish.
Human and Animal Cells Ba/F3(RCB0805) Novel Mechanism by a Bis-Pyridinium Fullerene Derivative to Induce Apoptosis by Enhancing the MEK-ERK Pathway in a Reactive Oxygen Species-Independent Manner in BCR-ABL-Positive Chronic Myeloid Leukemia-Derived K562 Cells.
Human and Animal Cells TE-8(RCB2098) , TE-9(RCB1988) , TE-15(RCB1951) GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways.
Human and Animal Cells KGN(RCB1154) Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway.
Human and Animal Cells Hep G2 (-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways.
Human and Animal Cells StromaNKtert(RCB2350) Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma.
Human and Animal Cells RAW 264(RCB0535) Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways.
Human and Animal Cells StromaNKtert(RCB2350) BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia.
Human and Animal Cells B16 melanoma(RCB1283) Tokoronin Contained in Dioscorea tokoro Makino ex Miyabe Suppressed α-MSH-Induced Melanogenesis in B16 Cells via Suppression of Classical MAPK Pathway Activation.
Human and Animal Cells MG-63(RCB1890) Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X7-ROS-ASK1-p38 Axis in Microglial Cell Lines.
Human and Animal Cells MC3T3-E1(RCB1126) Ginsenoside Rh2(S) induces the differentiation and mineralization of osteoblastic MC3T3-E1 cells through activation of PKD and p38 MAPK pathways.
Human and Animal Cells IEC 6(RCB0993) Autophagy Deficiency Diminishes Indomethacin-Induced Intestinal Epithelial Cell Damage through Activation of the ERK/Nrf2/HO-1 Pathway.
Human and Animal Cells RAW 264(RCB0535) IL-35 and RANKL Synergistically Induce Osteoclastogenesis in RAW264 Mouse Monocytic Cells.
Human and Animal Cells ATDC5(RCB0565) Exogenous C-type natriuretic peptide therapy for impaired skeletal growth in a murine model of glucocorticoid treatment.
Human and Animal Cells K562(RCB0027) , HL60 , Jurkat , RPMI8226(RCB3010) , Raji Molecular targeting of inosine-5'-monophosphate dehydrogenase by FF-10501 promotes erythropoiesis via ROS/MAPK pathway.
Human and Animal Cells HuCCT1(RCB1960) , TFK-1(RCB2537) Targeting c-MET by Tivantinib through synergistic activation of JNK/c-jun pathway in cholangiocarcinoma.
Human and Animal Cells B16 F10(RCB2630) Pyruvic acid/ethyl pyruvate inhibits melanogenesis in B16F10 melanoma cells through PI3K/AKT, GSK3β, and ROS-ERK signaling pathways.
Human and Animal Cells NB1RGB(RCB0222) The plant alkaloid conophylline inhibits matrix formation of fibroblasts.
Human and Animal Cells MH7A(RCB1512) Synovial cell death is regulated by TNF-α-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1α.