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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Mechanistic Target of Rapamycin Complex 1)
生物種 リソース名 タイトル
線虫 tm1978 , tmC5 Biased regulation of protein synthesis and hypoxic death by a conditional raptor mutation.
ゼブラフィッシュ XIG8A Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins.
実験動物マウス RBRC02975 Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
遺伝子材料 p3xFLAG-CMV10-hTel2 (RDB19795) , p3xFLAG-CMV10-hTti1 (RDB19800) Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
遺伝子材料 pMXs-IP-EGFP-hATG13 (RDB19625) , pME18s-HA-hFIP200 (RDB19769) , pEGFP-C1-hAtg13 (RDB19770) , p3xFLAG-CMV10-hAtg13 (RDB19771) , p3xFLAG-CMV14-mULK1 (RDB19772) Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
ヒト・動物細胞 PC-3(RCB2145) Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function.
ヒト・動物細胞 ST2(RCB0224) Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.
ヒト・動物細胞 ATDC5(RCB0565) mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
ヒト・動物細胞 GSU(RCB2278) , TGBC11TKB(RCB1148) , SH-10-TC(RCB1940) , GSS(RCB2277) , HGC-27(RCB0500) , KE-39(RCB1434) , KE-97(RCB1435) , H-111-TC(RCB1884) , GCIY(RCB0555) Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.
ヒト・動物細胞 C2C12(RCB0987) Dietary protein decreases exercise endurance through rapamycin-sensitive suppression of muscle mitochondria.
線虫 tm1944 An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.
線虫 tm1944 Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans.
ヒト・動物細胞 MC3T3-E1(RCB1126) PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.
ヒト・動物細胞 Sq-1(RCB1905) , LK-2(RCB1970) , LC-1/sq(RCB0455) , EBC-1(RCB1965) , RERF-LC-AI(RCB0444) Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma.
ヒト・動物細胞 ATDC5(RCB0565) mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis.
遺伝子材料 pMRX-puro-HA-mouse PAT4 (RDB15392). Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4.
線虫 tm1027 , tm504 A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans.
線虫 tm1027 , tm504 , tm2182 , tm1996 A Lipid-TORC1 Pathway Promotes Neuronal Development and Foraging Behavior under Both Fed and Fasted Conditions in C. elegans.
ヒト・動物細胞 K562(RCB1897) , T24(RCB0431) Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.