Species
|
Resource
|
RRC ID
|
Title
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Journal
|
Published
|
Link
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Zebrafish
|
XIG8A
|
82784
|
Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins.
|
BMC Dev Biol |
2014-12-6 |
Pubmed
Full text
|
DNA material
|
p3xFLAG-CMV10-hTel2 (RDB19795)
,
p3xFLAG-CMV10-hTti1 (RDB19800)
|
73637
|
Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
|
J Biol Chem |
2010-6-25 |
Pubmed
Full text
|
DNA material
|
pMXs-IP-EGFP-hATG13 (RDB19625)
,
pME18s-HA-hFIP200 (RDB19769)
,
pEGFP-C1-hAtg13 (RDB19770)
,
p3xFLAG-CMV10-hAtg13 (RDB19771)
,
p3xFLAG-CMV14-mULK1 (RDB19772)
|
72405
|
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
|
Mol Biol Cell |
2009-4-1 |
Pubmed
Full text
|
Human and Animal Cells
|
PC-3(RCB2145)
|
70457
|
Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function.
|
Sci Rep |
2022-4-23 |
Pubmed
Full text
|
Human and Animal Cells
|
ST2(RCB0224)
|
64734
|
Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.
|
Bioessays |
2016-8-1 |
Pubmed
Full text
|
Human and Animal Cells
|
ATDC5(RCB0565)
|
62263
|
mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.
|
Nat Commun |
2016-4-4 |
Pubmed
Full text
|
Human and Animal Cells
|
Atg5^(+/+)MEF(RCB2710)
,
Atg5^(-/-)MEF(RCB2711)
|
62097
|
Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
|
J Biol Chem |
2014-5-2 |
Pubmed
Full text
|
Human and Animal Cells
|
GSU(RCB2278)
,
TGBC11TKB(RCB1148)
,
SH-10-TC(RCB1940)
,
GSS(RCB2277)
,
HGC-27(RCB0500)
,
KE-39(RCB1434)
,
KE-97(RCB1435)
,
H-111-TC(RCB1884)
,
GCIY(RCB0555)
|
61587
|
Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.
|
Cancer Sci |
2016-12-1 |
Pubmed
Full text
|
C.elegans
|
tm1944
|
53382
|
An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.
|
Cell |
2016-12-15 |
Pubmed
Full text
|
C.elegans
|
tm1944
|
53325
|
Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans.
|
PLoS Genet |
2016-8-1 |
Pubmed
Full text
|
Human and Animal Cells
|
MC3T3-E1(RCB1126)
|
51945
|
PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.
|
Exp Cell Res |
2017-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
Sq-1(RCB1905)
,
LK-2(RCB1970)
,
LC-1/sq(RCB0455)
,
EBC-1(RCB1965)
,
RERF-LC-AI(RCB0444)
|
51903
|
Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma.
|
Anticancer Res |
2016-11-1 |
Pubmed
Full text
|
Human and Animal Cells
|
ATDC5(RCB0565)
|
51848
|
mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis.
|
J Cell Biochem |
2017-4-1 |
Pubmed
Full text
|
DNA material
|
pMRX-puro-HA-mouse PAT4 (RDB15392).
|
49528
|
Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4.
|
EMBO Rep |
2013-5-1 |
Pubmed
Full text
|
C.elegans
|
tm1027
,
tm504
|
46249
|
A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans.
|
Elife |
2013-5-21 |
Pubmed
Full text
|
C.elegans
|
tm1027
,
tm504
,
tm2182
,
tm1996
|
45584
|
A Lipid-TORC1 Pathway Promotes Neuronal Development and Foraging Behavior under Both Fed and Fasted Conditions in C. elegans.
|
Dev Cell |
2015-5-4 |
Pubmed
Full text
|
Human and Animal Cells
|
K562(RCB1897)
,
T24(RCB0431)
|
45364
|
Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.
|
Sci Rep |
2014-11-6 |
Pubmed
Full text
|
Human and Animal Cells
|
Atg5^(+/+)MEF(RCB2710)
,
Atg5^(-/-)MEF(RCB2711)
|
44597
|
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
|
Nat Cell Biol |
2013-10-1 |
Pubmed
Full text
|
Human and Animal Cells
|
OCUB-F(RCB0882)
|
44560
|
mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.
|
Sci Transl Med |
2013-7-31 |
Pubmed
Full text
|
Human and Animal Cells
|
PC-12(RCB0009)
|
44212
|
Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells.
|
J Pharmacol Sci |
2013-1-1 |
Pubmed
Full text
|