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  • 検索条件 : 絞込み (MeSH = Mechanistic Target of Rapamycin Complex 1)
生物種 リソース名 タイトル
遺伝子材料 p3xFLAG-CMV10-hTel2 (RDB19795) , p3xFLAG-CMV10-hTti1 (RDB19800) Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
遺伝子材料 pMXs-IP-EGFP-hATG13 (RDB19625) , pME18s-HA-hFIP200 (RDB19769) , pEGFP-C1-hAtg13 (RDB19770) , p3xFLAG-CMV10-hAtg13 (RDB19771) , p3xFLAG-CMV14-mULK1 (RDB19772) Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
ヒト・動物細胞 PC-3(RCB2145) Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function.
ヒト・動物細胞 ST2(RCB0224) Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.
ヒト・動物細胞 ATDC5(RCB0565) mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
ヒト・動物細胞 GSU(RCB2278) , TGBC11TKB(RCB1148) , SH-10-TC(RCB1940) , GSS(RCB2277) , HGC-27(RCB0500) , KE-39(RCB1434) , KE-97(RCB1435) , H-111-TC(RCB1884) , GCIY(RCB0555) Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells.
線虫 tm1944 An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.
線虫 tm1944 Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans.
ヒト・動物細胞 MC3T3-E1(RCB1126) PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.
ヒト・動物細胞 Sq-1(RCB1905) , LK-2(RCB1970) , LC-1/sq(RCB0455) , EBC-1(RCB1965) , RERF-LC-AI(RCB0444) Inhibition of Glutaminolysis Inhibits Cell Growth via Down-regulating Mtorc1 Signaling in Lung Squamous Cell Carcinoma.
ヒト・動物細胞 ATDC5(RCB0565) mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis.
遺伝子材料 pMRX-puro-HA-mouse PAT4 (RDB15392). Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4.
線虫 tm1027 , tm504 A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans.
線虫 tm1027 , tm504 , tm2182 , tm1996 A Lipid-TORC1 Pathway Promotes Neuronal Development and Foraging Behavior under Both Fed and Fasted Conditions in C. elegans.
ヒト・動物細胞 K562(RCB1897) , T24(RCB0431) Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
ヒト・動物細胞 OCUB-F(RCB0882) mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.
ヒト・動物細胞 PC-12(RCB0009) Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells.
ヒト・動物細胞 Blockade of adipocyte differentiation by cordycepin.