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生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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実験動物マウス
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RBRC04495
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88446
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Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation.
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J Exp Clin Cancer Res |
2020-11-30 |
Pubmed
Full text
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実験動物マウス
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RBRC03952
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88289
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mTORC1 accelerates retinal development via the immunoproteasome.
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Nat Commun |
2018-6-27 |
Pubmed
Full text
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酵母
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83115
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PP2A promotes ESCRT-0 complex formation on vacuolar membranes and microautophagy induction after TORC1 inactivation.
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Biochem Biophys Res Commun |
2020-4-9 |
Pubmed
Full text
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酵母
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83111
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Cdc14 phosphatase downmodulates ESCRT-0 complex formation on vacuolar membranes and microautophagy after TORC1 inactivation.
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Biochem Biophys Res Commun |
2021-7-5 |
Pubmed
Full text
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実験動物マウス
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RBRC00806
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82622
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Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.
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J Clin Invest |
2017-12-1 |
Pubmed
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線虫
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tm4397
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tm4212
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76065
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ATF-4 and hydrogen sulfide signalling mediate longevity in response to inhibition of translation or mTORC1.
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Nat Commun |
2022-2-18 |
Pubmed
Full text
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線虫
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tm6026
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76046
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Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
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Aging Cell |
2021-10-1 |
Pubmed
Full text
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ショウジョウバエ
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DGRC#104863
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70850
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A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.
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Elife |
2021-5-14 |
Pubmed
Full text
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ゼブラフィッシュ
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Tg(vglut2a:loxP-DsRed-loxP-GFP)
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70311
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
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Cell |
2021-2-4 |
Pubmed
Full text
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ヒト・動物細胞
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293(RCB1637)
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68863
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Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays.
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Int J Mol Sci |
2021-8-16 |
Pubmed
Full text
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ヒト・動物細胞
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C2C12(RCB0987)
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67578
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The involvement of Sestrin2 in the effect of IGF-I and leucine on mTROC1 activity in C2C12 and L6 myocytes.
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Growth Horm IGF Res |
2021-8-1 |
Pubmed
Full text
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ショウジョウバエ
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5671R-2
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64352
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Differential metabolic sensitivity of insulin-like-response- and TORC1-dependent overgrowth in Drosophila fat cells.
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Genetics |
2021-3-3 |
Pubmed
Full text
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ヒト・動物細胞
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NOS-1(RCB1032)
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63636
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Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma.
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Cell Rep |
2021-1-26 |
Pubmed
Full text
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ショウジョウバエ
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10539R-2
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61885
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Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes.
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Development |
2021-1-10 |
Pubmed
Full text
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ショウジョウバエ
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5520R-1
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18255R-1
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31014R-2
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9726R-1
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31015R-1
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61045
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Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.
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Mol Cells |
2020-8-31 |
Pubmed
Full text
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線虫
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tm1133
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tm1108
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59633
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Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
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Elife |
2019-8-14 |
Pubmed
Full text
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線虫
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tm4931
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tm4642
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59484
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The Rheb-TORC1 signaling axis functions as a developmental checkpoint.
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Development |
2020-3-2 |
Pubmed
Full text
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酵母
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FY9908
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FY9910
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FY21019
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58218
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Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
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Aging Cell |
2020-2-1 |
Pubmed
Full text
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遺伝子材料
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pCAG-HIVgp (RDB04394)
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pCMV-VSV-G-RSV-Rev (RDB04393)
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56703
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Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages.
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Cell Rep |
2017-11-28 |
Pubmed
Full text
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線虫
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tm6608
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56245
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mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation.
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Cell |
2018-9-6 |
Pubmed
Full text
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