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  • Search Condition : Filter (MeSH = Methyltransferases / genetics)
Species Resource Title
Drosophila 10009Ab-1 Mettl1-dependent m7G tRNA modification is essential for maintaining spermatogenesis and fertility in Drosophila melanogaster.
C.elegans tm6870 , tm6890 Characterization of the biochemical activity and tumor-promoting role of the dual protein methyltransferase METL-13/METTL13 in Caenorhabditis elegans.
Yeast Euchromatin factors HULC and Set1C affect heterochromatin organization and mating-type switching in fission yeast Schizosaccharomyces pombe.
Barley Proctor , Malaini Hordeum vulgare CYP76M57 catalyzes C2 shortening of tryptophan side chain by C–N bond rearrangement in gramine biosynthesis
Human and Animal Cells RAW 264(RCB0535) Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism.
C.elegans tm1489 , tm1624 , tm3746 , tm1818 , tm2963 , tm760 H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans.
C.elegans tm4477 , tm869 pre-piRNA trimming and 2'-O-methylation protect piRNAs from 3' tailing and degradation in C. elegans.
Human and Animal Cells HuH-7 Adenosine N6-methylation upregulates the expression of human CYP2B6 by altering the chromatin status.
Human and Animal Cells LC-2/ad(RCB0440) m6A RNA methylation regulates the transcription factors JUN and JUNB in TGF-β-induced epithelial-mesenchymal transition of lung cancer cells.
Algae NIES-2145 Betaine Lipid Is Crucial for Adapting to Low Temperature and Phosphate Deficiency in Nannochloropsis.
Human and Animal Cells Hep G2 m6A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2.
Arabidopsis / Cultured plant cells, genes pst00546 , pst10798 A carlactonoic acid methyltransferase that contributes to the inhibition of shoot branching in Arabidopsis.
Human and Animal Cells KP4(RCB1005) SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy.
General Microbes JCM20922 Identification of a Unique Type of Isoflavone O-Methyltransferase, GmIOMT1, Based on Multi-Omics Analysis of Soybean under Biotic Stress.
Drosophila pBFv-U6.2 Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
Human and Animal Cells T3M-4(RCB1021) METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
Drosophila DGRC#140400 Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.
C.elegans tm4924 , tm4529 , tm4547 , tm4627 The kynurenine pathway is essential for rhodoquinone biosynthesis in Caenorhabditis elegans.
Human and Animal Cells LC-2/ad(RCB0440) , A549 The m6A methyltransferase METTL3 contributes to Transforming Growth Factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the regulation of JUNB.
Human and Animal Cells Huh-7 Methylation of adenosine at the N6 position post-transcriptionally regulates hepatic P450s expression.