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  • 検索条件 : 絞込み (MeSH = Motor Neurons / pathology*)
生物種 リソース名 タイトル
ゼブラフィッシュ Tg[UAS:mRFP1-TDP-43z] , Tg[UAS:mRFP1-CRY2olig] , Tg[UAS:opTDP-43z] , Tg[mnr2b-hs:EGFP-TDP-43z] , Tg[mnr2b-hs:opTDP-43h] , Tg[mnr2b-hs:opTDP-43hA315T] Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons.
線虫 tm776 Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
ショウジョウバエ Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
ゼブラフィッシュ Tg(CM-isl1:GFP) Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.
線虫 tm1689 Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.
ゼブラフィッシュ Tg(Huc:Kaede) ALS-linked protein disulfide isomerase variants cause motor dysfunction.
実験動物マウス RBRC00806 In vivo optical imaging of motor neuron autophagy in a mouse model of amyotrophic lateral sclerosis.
ラット TRM/Kyo(strainID=11) Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease.