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  • 検索条件 : 絞込み (MeSH = Neurodegenerative Diseases / genetics)
生物種 リソース名 タイトル
線虫 tm1779 Mitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases.
実験動物マウス RBRC06334 Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
ショウジョウバエ Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models.
ショウジョウバエ Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
線虫 tm6026 Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
線虫 tm1116 , tm1489 The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2.
線虫 tm1175 , tm10457 CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease.
線虫 tm813 Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation.
線虫 tm1325 , tm1548 Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans.
線虫 tm1779 Mitochondrial Uncoupling Attenuates Age-Dependent Neurodegeneration in C. elegans.
実験動物マウス RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
線虫 tm4189 , tm4127 , tm3933 , tm4845 , tm4391 , tm4516 CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
ショウジョウバエ 13387R-1 , 13387R-4 Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
ショウジョウバエ Bax-like protein Drob-1 protects neurons from expanded polyglutamine-induced toxicity in Drosophila.
ショウジョウバエ Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.
ショウジョウバエ Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration.