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論文 - 一覧

  • 21 Hits
  • 検索条件 : 絞込み (MeSH = Neurodegenerative Diseases / pathology)
生物種 リソース名 タイトル
実験動物マウス RBRC01386 Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases.
ゼブラフィッシュ UAS:BoTxBLCGFP, UAS:GCaMP7a Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.
ショウジョウバエ DGRC#107715 α-Synuclein pathology in Drosophila melanogaster is exacerbated by haploinsufficiency of Rop: connecting STXBP1 encephalopathy with α-synucleinopathies.
線虫 tm6026 Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
ヒト・動物細胞 U251(RCB0461) Expression of alpha-synuclein in a human glioma cell line and its up-regulation by interleukin-1beta.
線虫 tm5210 Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.
実験動物マウス RBRC06334 Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
ヒト・動物細胞 KG-1-C(RCB0270) Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.
ヒト・動物細胞 MC3T3-G2/PA6(RCB1127) Neural differentiation of induced pluripotent stem cells.
ショウジョウバエ Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models.
ショウジョウバエ Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
線虫 tm985 , tm1978 , tm4450 Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
ショウジョウバエ 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
線虫 tm813 Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation.
実験動物マウス RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
実験動物マウス RBRC01345 Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice.
ショウジョウバエ DGRC#105467 A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
実験動物マウス RBRC00388 Analysis of the protective effects of the α2/δ subunit of voltage-gated Ca2+ channels in brain injury.
線虫 tm4189 , tm4127 , tm3933 , tm4845 , tm4391 , tm4516 CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
ショウジョウバエ Drosophila as a screening tool to study human neurodegenerative diseases.