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  • 14 Hits
  • Search Condition : Filter (MeSH = Neurodegenerative Diseases / pathology)
Species Resource Title
Human and Animal Cells KG-1-C(RCB0270) Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.
Human and Animal Cells MC3T3-G2/PA6(RCB1127) Neural differentiation of induced pluripotent stem cells.
Drosophila Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models.
Drosophila Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
C.elegans tm985 , tm1978 , tm4450 Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
Drosophila 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
C.elegans tm813 Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation.
Mice RBRC01390 Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Mice RBRC01345 Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice.
Drosophila DGRC#105467 A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
Mice RBRC00388 Analysis of the protective effects of the α2/δ subunit of voltage-gated Ca2+ channels in brain injury.
C.elegans tm4189 , tm4127 , tm3933 , tm4845 , tm4391 , tm4516 CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Drosophila Drosophila as a screening tool to study human neurodegenerative diseases.
Drosophila Bax-like protein Drob-1 protects neurons from expanded polyglutamine-induced toxicity in Drosophila.