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18 Hits
検索条件 : 絞込み (MeSH = Neurodegenerative Diseases / pathology)
生物種
リソース名
RRC ID
タイトル
ジャーナル
公開日
外部リンク
線虫
tm6026
76046
Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
Aging Cell
2021-10-1
Pubmed
Full text
ヒト・動物細胞
U251(RCB0461)
72295
Expression of alpha-synuclein in a human glioma cell line and its up-regulation by interleukin-1beta.
Neuroreport
2001-7-3
Pubmed
Full text
線虫
tm5210
65377
Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.
PLoS Genet
2021-3-1
Pubmed
Full text
実験動物マウス
RBRC06334
62271
Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
J Neuroinflammation
2020-12-14
Pubmed
Full text
ヒト・動物細胞
KG-1-C(RCB0270)
62044
Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy.
Mol Neurodegener
2012-8-14
Pubmed
Full text
ヒト・動物細胞
MC3T3-G2/PA6(RCB1127)
61855
Neural differentiation of induced pluripotent stem cells.
Methods Mol Biol
2011-1-1
Pubmed
Full text
ショウジョウバエ
60791
Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models.
PLoS One
2009-1-1
Pubmed
Full text
ショウジョウバエ
60789
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases.
Nat Cell Biol
2007-4-1
Pubmed
Full text
線虫
tm985
,
tm1978
,
tm4450
59457
Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
PLoS Genet
2019-8-1
Pubmed
Full text
ショウジョウバエ
8203R-1
56660
Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
Hum Mol Genet
2019-9-15
Pubmed
Full text
線虫
tm813
54286
Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation.
Mol Cell
2017-3-16
Pubmed
Full text
実験動物マウス
RBRC01390
50066
Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Neurobiol Aging
2018-3-1
Pubmed
Full text
実験動物マウス
RBRC01345
49640
Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice.
Glia
2018-4-1
Pubmed
Full text
ショウジョウバエ
DGRC#105467
47654
A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
Neurobiol Dis
2017-2-1
Pubmed
Full text
実験動物マウス
RBRC00388
47308
Analysis of the protective effects of the α
2
/δ subunit of voltage-gated Ca
2+
channels in brain injury.
Brain Res
2017-1-15
Pubmed
Full text
線虫
tm4189
,
tm4127
,
tm3933
,
tm4845
,
tm4391
,
tm4516
46062
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Ann Neurol
2013-7-1
Pubmed
Full text
ショウジョウバエ
28877
Drosophila as a screening tool to study human neurodegenerative diseases.
J Neurochem
2013-11-1
Pubmed
Full text
ショウジョウバエ
11562
Bax-like protein Drob-1 protects neurons from expanded polyglutamine-induced toxicity in Drosophila.
EMBO J
2005-7-20
Pubmed
Full text