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  • Search Condition : Filter (MeSH = Osteoarthritis / genetics)
Species Resource Title
Human and Animal Cells HeLa(RCB0007) Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage.
Human and Animal Cells ATDC5(RCB0565) Tumor Necrosis Factor Receptor Associated Factor 3 Modulates Cartilage Degradation through Suppression of Interleukin 17 Signaling.
Human and Animal Cells ATDC5(RCB0565) Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling.
Human and Animal Cells ATDC5(RCB0565) Fibulin-4 reduces extracellular matrix production and suppresses chondrocyte differentiation via DKK1- mediated canonical Wnt/β-catenin signaling.
Human and Animal Cells ATDC5(RCB0565) C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.
Human and Animal Cells ATDC5(RCB0565) A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis.
Human and Animal Cells 10T1/2(RCB0247) , ATDC5(RCB0565) Runx1 contributes to articular cartilage maintenance by enhancement of cartilage matrix production and suppression of hypertrophic differentiation.
Human and Animal Cells 10T1/2(RCB0247) Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.
Human and Animal Cells ATDC5(RCB0565) RETRACTED: Notoginsenoside R1 suppresses miR-301a via NF-κB pathway in lipopolysaccharide-treated ATDC5 cells.
Human and Animal Cells ATDC5(RCB0565) lncRNA‑NR024118 overexpression reverses LPS‑induced inflammatory injury and apoptosis via NF‑κB/Nrf2 signaling in ATDC5 chondrocytes.
Human and Animal Cells ATDC5(RCB0565) Long noncoding RNA CHRF exacerbates IL-6-induced inflammatory damages by downregulating microRNA-146a in ATDC5 cells.
Human and Animal Cells ATDC5(RCB0565) Long non-coding RNA highly up-regulated in liver cancer protects tumor necrosis factor-alpha-induced inflammatory injury by down-regulation of microRNA-101 in ATDC5 cells.
Human and Animal Cells ATDC5(RCB0565) Halofuginone attenuates articular cartilage degeneration by inhibition of elevated TGF‑β1 signaling in articular cartilage in a rodent osteoarthritis model.
Human and Animal Cells ATDC5(RCB0565) Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes.
Human and Animal Cells MKN45(RCB1001) Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis.
Human and Animal Cells ATDC5(RCB0565) Human YKL39 (chitinase 3-like protein 2), an osteoarthritis-associated gene, enhances proliferation and type II collagen expression in ATDC5 cells.
Human and Animal Cells ATDC5(RCB0565) SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways.
Human and Animal Cells Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis.
Mice , Human and Animal Cells RBRC01071 , ATDC5(RCB0565) , HeLa Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.
Human and Animal Cells ATDC5(RCB0565) Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice.