Species
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Resource
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RRC ID
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Title
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Journal
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Published
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Link
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Human and Animal Cells
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NUGC-4(RCB1939)
,
MKN7(RCB0999)
,
MKN45(RCB1001)
|
78647
|
ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.
|
Gastric Cancer |
2023-5-1 |
Pubmed
Full text
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Human and Animal Cells
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Lu-134-A(RCB0466)
,
Lu-134-B(RCB0467)
|
77180
|
Targeting small cell lung cancer harboring PIK3CA mutation with a selective oral PI3K inhibitor PF-4989216.
|
Clin Cancer Res |
2014-2-1 |
Pubmed
Full text
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Human and Animal Cells
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MDCK(RCB0995)
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73006
|
Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
|
Biochem Biophys Res Commun |
2002-2-1 |
Pubmed
Full text
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Human and Animal Cells
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NIH/3T3(RCB2767)
|
72834
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KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.
|
Dev Cell |
2022-10-10 |
Pubmed
Full text
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DNA material
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pEGFP-C1-hUVRAG (RDB19632)
,
pMXs-puro-VPS34-GFP (RDB19633)
,
p3xFLAG-CMV10-hUVRAG (RDB19776)
,
pEGFP-C1-hAtg14 (RDB19785)
,
pMXs-IP-GFP-Atg14 (RDB19790)
,
pCI-neo-HA-hAtg14 (RDB19797)
,
pCI-neo-HA-hUVRAG (RDB19803)
|
72404
|
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.
|
Mol Biol Cell |
2008-12-1 |
Pubmed
Full text
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Human and Animal Cells
|
MKN45(RCB1001)
,
MKN74(RCB1002)
|
66084
|
Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.
|
Sci Rep |
2017-5-23 |
Pubmed
Full text
|
Human and Animal Cells
|
Hep G2
|
65616
|
(-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways.
|
Anticancer Res |
2017-11-1 |
Pubmed
Full text
|
Human and Animal Cells
|
JHOC-5(RCB1520)
|
65432
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A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation.
|
BMC Cancer |
2014-2-22 |
Pubmed
Full text
|
Yeast
|
|
64325
|
TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation.
|
Nat Cell Biol |
2021-3-1 |
Pubmed
Full text
|
Human and Animal Cells
|
RAW 264(RCB0535)
|
62966
|
Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.
|
Toxicology |
2020-10-1 |
Pubmed
Full text
|
Human and Animal Cells
|
Ca9-22(RCB1976)
,
HSC-2(RCB1945)
,
HSC-4(RCB1902)
,
Sa3(RCB0980)
,
HSQ-89(RCB0789)
,
SAS(RCB1974)
,
HO-1-u-1(RCB2102)
|
62782
|
Loss of NDRG2 Expression Confers Oral Squamous Cell Carcinoma with Enhanced Metastatic Potential.
|
Cancer Res |
2017-5-1 |
Pubmed
Full text
|
Human and Animal Cells
|
HSC-4(RCB1902)
,
SAS(RCB1974)
,
Ca9-22(RCB1976)
|
61824
|
Migration of oral squamous cell carcinoma cells are induced by HGF/c-Met signalling via lamellipodia and filopodia formation.
|
Oncol Rep |
2017-6-1 |
Pubmed
Full text
|
Human and Animal Cells
|
HKBML(RCB0820)
|
61807
|
Metabolome Analysis Reveals Excessive Glycolysis via PI3K/AKT/mTOR and RAS/MAPK Signaling in Methotrexate-Resistant Primary CNS Lymphoma-Derived Cells.
|
Clin Cancer Res |
2020-6-1 |
Pubmed
Full text
|
Human and Animal Cells
|
JHOC-5(RCB1520)
,
JHOC-7(RCB1688)
,
JHOC-8(RCB1723)
,
JHOC-9(RCB2226)
|
61806
|
Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis.
|
PLoS One |
2013-1-1 |
Pubmed
Full text
|
Human and Animal Cells
|
HeLa(RCB0007)
,
Saos-2(RCB0428)
|
61244
|
Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways.
|
Development |
2011-4-1 |
Pubmed
Full text
|
Human and Animal Cells
|
iPS-MEF-Ng-20D-17(APS0001)
|
60953
|
Signaling Inhibitors Accelerate the Conversion of mouse iPS Cells into Cancer Stem Cells in the Tumor Microenvironment.
|
Sci Rep |
2020-6-22 |
Pubmed
Full text
|
Drosophila
|
|
58476
|
Ras2, the TC21/R-Ras2 Drosophila homologue, contributes to insulin signalling but is not required for organism viability.
|
Dev Biol |
2020-5-15 |
Pubmed
Full text
|
Human and Animal Cells
|
TE-1(RCB1894)
,
TE-8(RCB2098)
,
TE-10(RCB2099)
,
TE-11(RCB2100)
|
56636
|
B7H4 is associated with stemness and cancer progression in esophageal squamous cell carcinoma.
|
Hum Pathol |
2018-10-1 |
Pubmed
Full text
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Human and Animal Cells
|
A549
|
55912
|
Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells.
|
Biochim Biophys Acta Mol Cell Res |
2018-5-1 |
Pubmed
Full text
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Cellular slime molds
|
|
54935
|
Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells.
|
J Cell Sci |
2019-3-4 |
Pubmed
Full text
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