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  • Search Condition : Filter (MeSH = Phosphatidylinositol 3-Kinases / genetics)
Species Resource Title
Human and Animal Cells JHOC-5(RCB1520) A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation.
Human and Animal Cells RAW 264(RCB0535) Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production.
Human and Animal Cells Ca9-22(RCB1976) , HSC-2(RCB1945) , HSC-4(RCB1902) , Sa3(RCB0980) , HSQ-89(RCB0789) , SAS(RCB1974) , HO-1-u-1(RCB2102) Loss of NDRG2 Expression Confers Oral Squamous Cell Carcinoma with Enhanced Metastatic Potential.
Human and Animal Cells HSC-4(RCB1902) , SAS(RCB1974) , Ca9-22(RCB1976) Migration of oral squamous cell carcinoma cells are induced by HGF/c-Met signalling via lamellipodia and filopodia formation.
Human and Animal Cells JHOC-5(RCB1520) , JHOC-7(RCB1688) , JHOC-8(RCB1723) , JHOC-9(RCB2226) Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis.
Human and Animal Cells HeLa(RCB0007) , Saos-2(RCB0428) Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways.
Human and Animal Cells A549 Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells.
Cellular slime molds Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells.
Human and Animal Cells MRC-5(RCB0211) Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer.
Human and Animal Cells CACO-2(RCB0988) Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-κB signaling pathway in secondary hyperparathyroidism.
Human and Animal Cells MKN1(RCB1003) Analysis of PIK3CA mutations and PI3K pathway proteins in advanced gastric cancer.
Human and Animal Cells MKN1(RCB1003) , MKN45(RCB1001) , MKN7(RCB0999) , MKN74(RCB1002) PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma.
Mice RBRC01834 Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
C.elegans tm3536 , tm3645 Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling in Caenorhabditis elegans.
C.elegans tm331 , tm420 DAF-16 and Δ9 desaturase genes promote cold tolerance in long-lived Caenorhabditis elegans age-1 mutants.
C.elegans tm4475 PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation.
C.elegans tm1956 The insulin/IGF signaling regulators cytohesin/GRP-1 and PIP5K/PPK-1 modulate susceptibility to excitotoxicity in C. elegans.
C.elegans tm718 Role of synaptic phosphatidylinositol 3-kinase in a behavioral learning response in C. elegans.
C.elegans tm2423 PtdIns(4,5)P₂ and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance.
Human and Animal Cells Acidic pH increases cGMP accumulation through the OGR1/phospholipase C/Ca(2+)/neuronal NOS pathway in N1E-115 neuronal cells.