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  • Search Condition : Filter (MeSH = Phosphatidylinositol 3-Kinases / metabolism)
Species Resource Title
Zebrafish XIG8A Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins.
Human and Animal Cells Colon-26(RCB2657) Mannose-methyl-β-cyclodextrin suppresses tumor growth by targeting both colon cancer cells and tumor-associated macrophages.
Human and Animal Cells MIA Paca2(RCB2094) , PANC-1(RCB2095) FOXO3a Activation by HDAC Class IIa Inhibition Induces Cell Cycle Arrest in Pancreatic Cancer Cells.
Human and Animal Cells MH7A(RCB1512) FGF23 facilitates IL-1β synthesis in rheumatoid arthritis through activating PI3K, Akt, and NF-κB pathways.
Prokaryotes E. coli Short‐chain fatty acids stimulate dendrite elongation in dendritic cells by inhibiting histone deacetylase
Human and Animal Cells NUGC-4(RCB1939) , MKN7(RCB0999) , MKN45(RCB1001) ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.
Human and Animal Cells Kato III(RCB2088) , NUGC-4(RCB1939) , HGC-27(RCB0500) , MKN7(RCB0999) , MKN28(RCB1000) , MKN45(RCB1001) , MKN74(RCB1002) , WI-38(RCB0702) Overexpression of Tetraspanin31 contributes to malignant potential and poor outcomes in gastric cancer.
Human and Animal Cells TE-14(RCB2101) , TE-6(RCB1950) , TE-8(RCB2098) , TE-5(RCB1949) , TE-11(RCB2100) , TE-15(RCB1951) , TE-4(RCB2097) , TE-1(RCB1894) , TE-10(RCB2099) , TE-9(RCB1988) , ... Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors.
Human and Animal Cells HuH-7(RCB1366) Curcumin-Mediated Resistance to Lenvatinib via EGFR Signaling Pathway in Hepatocellular Carcinoma.
DNA material p3xFLAG-CMV10-hTel2 (RDB19795) , p3xFLAG-CMV10-hTti1 (RDB19800) Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
Human and Animal Cells MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Human and Animal Cells SK-MEL-28(RCB1930) , G-361(RCB0991) , C32TG(RCB1929) VEGF-A promotes the motility of human melanoma cells through the VEGFR1-PI3K/Akt signaling pathway.
Human and Animal Cells Kato III(RCB2088) , MKN1(RCB1003) , MKN-7(RCB3687) , MKN45(RCB1001) MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target.
Human and Animal Cells iPS-MEF-Ng-20D-17(APS0001) Cancer stem cells induced by chronic stimulation with prostaglandin E2 exhibited constitutively activated PI3K axis.
DNA material pMXs-IP-GFP-WIPI1 (RDB19630) , pMXs-puro-GFP-DFCP1 (RDB19637) , pMXs-IP spGFP-ERGIC53 (RDB19768) , pMXs-puro HA-WIPI-1 (RDB19788) Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells A549 Increase in Anticancer Drug-Induced Toxicity by Fisetin in Lung Adenocarcinoma A549 Spheroid Cells Mediated by the Reduction of Claudin-2 Expression.
General Microbes JCM2009 Surface-layer protein produced by Lactobacillus crispatus JCM 2009 ameliorates lipopolysaccharide-induced inflammation through autophagy cross-talk with the NF-κB signaling pathway.
Mice RBRC03163 Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis.
Human and Animal Cells MC3T3-E1(RCB1126) HIF-1α plays an essential role in BMP9-mediated osteoblast differentiation through the induction of a glycolytic enzyme, PDK1.