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  • 149 Hits
  • Search Condition : Filter (MeSH = Phosphatidylinositol 3-Kinases / metabolism)
Species Resource Title
DNA material p3xFLAG-CMV10-hTel2 (RDB19795) , p3xFLAG-CMV10-hTti1 (RDB19800) Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
Human and Animal Cells MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Human and Animal Cells SK-MEL-28(RCB1930) , G-361(RCB0991) , C32TG(RCB1929) VEGF-A promotes the motility of human melanoma cells through the VEGFR1-PI3K/Akt signaling pathway.
Human and Animal Cells Kato III(RCB2088) , MKN1(RCB1003) , MKN-7(RCB3687) , MKN45(RCB1001) MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target.
Human and Animal Cells iPS-MEF-Ng-20D-17(APS0001) Cancer stem cells induced by chronic stimulation with prostaglandin E2 exhibited constitutively activated PI3K axis.
DNA material pMXs-IP-GFP-WIPI1 (RDB19630) , pMXs-puro-GFP-DFCP1 (RDB19637) , pMXs-IP spGFP-ERGIC53 (RDB19768) , pMXs-puro HA-WIPI-1 (RDB19788) Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells A549 Increase in Anticancer Drug-Induced Toxicity by Fisetin in Lung Adenocarcinoma A549 Spheroid Cells Mediated by the Reduction of Claudin-2 Expression.
General Microbes JCM2009 Surface-layer protein produced by Lactobacillus crispatus JCM 2009 ameliorates lipopolysaccharide-induced inflammation through autophagy cross-talk with the NF-κB signaling pathway.
Mice RBRC03163 Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis.
Human and Animal Cells MC3T3-E1(RCB1126) HIF-1α plays an essential role in BMP9-mediated osteoblast differentiation through the induction of a glycolytic enzyme, PDK1.
Human and Animal Cells PC-3(RCB2145) , DU145(RCB2143) Tenascin C regulates cancer cell glycolysis and tumor progression in prostate cancer.
Human and Animal Cells KGN(RCB1154) HGF Secreted by Mesenchymal Stromal Cells Promotes Primordial Follicle Activation by Increasing the Activity of the PI3K-AKT Signaling Pathway.
Human and Animal Cells A20(RCB2745) Immunoglobulin a suppresses B cell receptor-mediated activation of mouse B cells with differential inhibition of signaling molecules.
Human and Animal Cells iPSC line Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells.
Human and Animal Cells RAW 264(RCB0535) Reduced scytonemin isolated from Nostoc commune suppresses LPS/IFNγ-induced NO production in murine macrophage RAW264 cells by inducing hemeoxygenase-1 expression via the Nrf2/ARE pathway.
Human and Animal Cells CW-2(RCB0778) Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.
Human and Animal Cells HSC-2(RCB1945) ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.
Human and Animal Cells Hep G2 Effects of Ursodeoxycholic Acid and Insulin on Palmitate-Induced ROS Production and Down-Regulation of PI3K/Akt Signaling Activity.