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  • Search Condition : Filter (MeSH = Proteasome Endopeptidase Complex / metabolism)
Species Resource
C.elegans tm808 The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line.
C.elegans tm3886 , tm853 DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.
Arabidopsis / Cultured plant cells, genes rpc00001 Environmental stresses induce misfolded protein aggregation in plant cells in a microtubule-dependent manner.
DNA material pRSFlag_mmSumo1 (RDB06126) Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.
Mice 129-Sirt1<tm1Mcby>(RBRC05323) Sirt1-deficiency causes defective protein quality control.
Human and Animal Cells Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase.
Human and Animal Cells Rapid downregulation of cyclin D1 induced by geranylgeranoic acid in human hepatoma cells.
Human and Animal Cells Reversible induction of PARP1 degradation by p53-inducible cis-imidazoline compounds.
Human and Animal Cells Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Yeast BYP1804 The Ubiquitin Ligase SCF(Ucc1) Acts as a Metabolic Switch for the Glyoxylate Cycle.
Yeast ? Recent technical developments in the study of ER-associated degradation.
Medaka FLFII (MT109) , STII , Hd-rR.Y^HNI (MT191) Tunable Protein Stabilization In Vivo Mediated by Shield-1 in Transgenic Medaka.
Zebrafish SAIGFF213A , UASGCaMP7a32A? , UASRFP1A ? RING finger protein 121 facilitates the degradation and membrane localization of voltage-gated sodium channels.
Pathogenic microorganisms ? The Ubiquitin Ligase SCF(Ucc1) Acts as a Metabolic Switch for the Glyoxylate Cycle.
Arabidopsis / Cultured plant cells, genes rpc00001 Characterization of terfestatin A, a new specific inhibitor for auxin signaling.
Human and Animal Cells HuH-7 (RCB1366) CHO-K1 (RCB0285) Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport.
Human and Animal Cells , DNA material 293T (RCB2202) , HeLa (RCB0007) , pAxCALNLmAREC3 (forward) (RDB02405) , GST-Fyn SH3 Fyn SH3 domain (RDB02120) , pAxCALNLmSIX2 (reverse) (RDB02402) Quantitative cell-based protein degradation assays to identify and classify drugs that target the ubiquitin-proteasome system.
Human and Animal Cells NB2a (RCB2639) Derlin-1 overexpression ameliorates mutant SOD1-induced endoplasmic reticulum stress by reducing mutant SOD1 accumulation.
Human and Animal Cells PC-12 (RCB0009) The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease.
Human and Animal Cells RAW 264 (RCB0535) Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.