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  • Search Condition : Filter (MeSH = Protein Aggregates)
Species Resource
DNA material CMV:TDP43-GFP (RDB15742) , CMV:GFP-TDP25 (RDB15743) , CMV:GFP-NLS-TDP25 (RDB15744) , CMV:GFP-NLSNP-TDP25 (RDB15745) , GFP-NLS NP (RDB15746) , mCherry-Ubiquitin (RDB15747). Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.
DNA material IRAL010J08 (HGY084224) Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation.
C.elegans tm5219 A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan.
C.elegans tm1297 , tm2149 Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity.
Drosophila 5680R-2 Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.
Drosophila DGRC#140400 Small heat shock proteins mediate cell-autonomous and -nonautonomous protection in a Drosophila model for environmental-stress-induced degeneration.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) , A549(RCB0098) Formation of high molecular weight p62 by CORM-3.
Human and Animal Cells iPS-MEF-Ng-178B-5(APS0002) , iPS-MEF-FB/Ng-440A-3(APS0003) In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea.