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Human and Animal Cells HPS0097(HPS0097) , 454E2(HPS0077) Loss of intracellular ATP affects axoplasmic viscosity and pathological protein aggregation in mammalian neurons.
Human and Animal Cells , DNA material 293T(RCB2202) , CSII-EF-MCS (RDB04378) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates.
Yeast Rapamycin Abrogates Aggregation of Human α-Synuclein Expressed in Fission Yeast via an Autophagy-Independent Mechanism.
C.elegans tm4919 Effect of the mitochondrial unfolded protein response on hypoxic death and mitochondrial protein aggregation.
C.elegans tm4909 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
DNA material FL-linked EGFP dimer (RDB19236) , FL-linked EGFP trimer (RDB19237) , FL-linked EGFP tetramer (RDB19238) , FL-linked EGFP pentamer (RDB19239) Polarization-dependent fluorescence correlation spectroscopy for studying structural properties of proteins in living cell.
Human and Animal Cells KP4(RCB1005) , PK-1(RCB1972) Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.
Yeast FY34176 , FY34175 The Putative RNA-Binding Protein Dri1 Promotes the Loading of Kinesin-14/Klp2 to the Mitotic Spindle and Is Sequestered into Heat-Induced Protein Aggregates in Fission Yeast.
Human and Animal Cells 293T(RCB2202) AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG.
Human and Animal Cells 293(RCB1637) Mechanisms underlying the toxic effects of antimony species in human embryonic kidney cells (HEK-293) and their comparison with arsenic species.
Drosophila DGRC#110875 Cofilin Loss in Drosophila Muscles Contributes to Muscle Weakness through Defective Sarcomerogenesis during Muscle Growth.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) , pCAG-HIVgp (RDB04394) GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABAA receptor trafficking and social behavior.
Drosophila 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) , A549(RCB0098) Formation of high molecular weight p62 by CORM-3.
DNA material CMV:TDP43-GFP (RDB15742) , CMV:GFP-TDP25 (RDB15743) , CMV:GFP-NLS-TDP25 (RDB15744) , CMV:GFP-NLSNP-TDP25 (RDB15745) , GFP-NLS NP (RDB15746) , mCherry-Ubiquitin (RDB15747). Interaction of RNA with a C-terminal fragment of the amyotrophic lateral sclerosis-associated TDP43 reduces cytotoxicity.
Human and Animal Cells iPS-MEF-Ng-178B-5(APS0002) , iPS-MEF-Fb/Ng-440A-3(APS0003) In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea.
Drosophila DGRC#140400 Small heat shock proteins mediate cell-autonomous and -nonautonomous protection in a Drosophila model for environmental-stress-induced degeneration.
C.elegans tm1297 , tm2149 Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity.
C.elegans tm5219 A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan.
Drosophila 5680R-2 Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.