RRC ID 76035
Author Pras A, Houben B, Aprile FA, Seinstra R, Gallardo R, Janssen L, Hogewerf W, Gallrein C, De Vleeschouwer M, Mata-Cabana A, Koopman M, Stroo E, de Vries M, Louise Edwards S, Kirstein J, Vendruscolo M, Falsone SF, Rousseau F, Schymkowitz J, Nollen EAA.
Title The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
Journal EMBO J
Volume 40(21)
Pages e107568
Published 2021-11-2
DOI 10.15252/embj.2020107568
PMID 34617299
PMC PMC8561633
MeSH Amino Acid Sequence Amyloid / chemistry* Amyloid / genetics Amyloid / metabolism Amyloidogenic Proteins / chemistry* Amyloidogenic Proteins / genetics Amyloidogenic Proteins / metabolism Animals Binding Sites Caenorhabditis elegans / genetics* Caenorhabditis elegans / metabolism Caenorhabditis elegans Proteins / chemistry* Caenorhabditis elegans Proteins / genetics Caenorhabditis elegans Proteins / metabolism Gene Expression Regulation HEK293 Cells Humans Hydrophobic and Hydrophilic Interactions Intracellular Signaling Peptides and Proteins / chemistry* Intracellular Signaling Peptides and Proteins / genetics Intracellular Signaling Peptides and Proteins / metabolism Nerve Tissue Proteins / chemistry* Nerve Tissue Proteins / genetics Nerve Tissue Proteins / metabolism Peptides / genetics Peptides / metabolism Protein Aggregates Protein Array Analysis Protein Binding Signal Transduction Static Electricity alpha-Synuclein / chemistry* alpha-Synuclein / genetics alpha-Synuclein / metabolism
C.elegans tm4909