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  • 検索条件 : 絞込み (MeSH = Protein Serine-Threonine Kinases* / metabolism)
生物種 リソース名 タイトル
ショウジョウバエ CAS-0001 The Hippo tumor suppressor pathway triggers non-cell autonomous tumorigenesis in Drosophila.
酵母 FY21019 , FY32131 , FY21012 A tti1 mutation in the Tel2-Tti1-Tti2 complex specifically eliminates the cellular function of Rad3ATR, but not that of other PIKKs in fission yeast.
酵母 FY13012 , FY9954 A point mutation in the FAT domain constitutively increases the kinase activity of Rad3ATR and bypasses the requirement for 9-1-1 phosphorylation to activate the DNA replication checkpoint.
シロイヌナズナ / 植物培養細胞・遺伝子 rpc00001 IMK2-IMK3 module regulates biogenesis of nascent cell walls and postcytokinetic differentiation in Arabidopsis thaliana.
線虫 tm1524 BAF-1-VRK-1 mediated release of meiotic chromosomes from the nuclear periphery is important for genome integrity.
線虫 tm5353 The novel HRD motif kinase SPE-60 is required for sperm development and motility in Caenorhabditis elegans.
線虫 tm1416 , tm683 , tm1411 , tm5597 Neuroprotective role of Hippo signaling by microtubule stability control in Caenorhabditis elegans.
ゼブラフィッシュ UAS:GFP Transforming growth factor-β receptor I kinase plays a crucial role in oligodendrocyte regeneration after demyelination.
実験動物マウス RBRC01099 The Unfolded Protein Response Sensor IRE1 Regulates Activation of In Vitro Differentiated Type 1 Conventional DCs with Viral Stimuli.
実験動物マウス RBRC01099 The IRE1/XBP1s Axis Regulates Innate Immune Responses in Conventional Dendritic Cells During ZIKV Infection.
ショウジョウバエ 2128R-1 , 1770R-3 , 3119R-2 Reversible acetylation of Hpo regulates the Hippo pathway.
酵母 FY19706 Mutual, spatially limited control of meiotic DNA break formation by Mre11-Rad50-Nbs1 DNA repair complex and Tel1 (ATM) protein kinase.
ヒト・動物細胞 293T(RCB2202) Partial activation of salt-inducible kinase 3 delays the onset of wakefulness and alleviates hypersomnia due to the lack of protein kinase A-phosphorylation site.
ヒト・動物細胞 1231A3(HPS0381) iPSC-based drug discovery identified the Hippo signaling pathway as a therapeutic target in the fibrosis of NPHP1-deficient nephronophthisis.
ヒト・動物細胞 293T(RCB2202) , MG-63(RCB1890) PDK1-dependent metabolic reprogramming regulates stemness and tumorigenicity of osteosarcoma stem cells through ATF3.
実験動物マウス RBRC05515 IRE1α RNase activity is critical for early embryo development by degrading maternal transcripts.
酵母 FY24592 , FY40844 , FY13814 , FY8770 , FY24011 Balance of polo-like kinase Plo1 and monopolar attachment protein 1 (Moa1) regulates fission yeast meiosis.
線虫 tm2810 , tm1049 The MAST kinase KIN-4 carries out mitotic entry functions of Greatwall in C. elegans.
線虫 tm1395 , tm3298 Identification of the Polo-like kinase substrate required for homologous synapsis.
線虫 tm9715 , tmIs1219 , tmC20 , tm1458 Chemically induced proximity reveals a Piezo-dependent meiotic checkpoint at the oocyte nuclear envelope.