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  • Search Condition : Filter (MeSH = Protein Serine-Threonine Kinases / metabolism)
Species Resource Title
General Microbes JCM 18565 , JCM 17638 Live Mycobacterium paragordonae induces heterologous immunity of natural killer cells by eliciting type I interferons from dendritic cells via STING-dependent sensing of cyclic-di-GMP.
Medaka STII A rad50 germline mutation induces tumorigenesis and ataxia-telangiectasia phenotype in a transparent medaka model.
Drosophila DGRC#102258 , DGRC#102444 , DGRC#150224 Caspase cleaves Drosophila BubR1 to modulate spindle assembly checkpoint function and lifespan of the organism.
Human and Animal Cells HeLa , A549 CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockade.
Drosophila DGRC#115288 The Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism.
Human and Animal Cells EoL-1 cell(RCB0641) p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells.
C.elegans tm1779 Mitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases.
C.elegans tm351 , tm2427 , tm3023 , tm1880 , tm1888 , tm1983 , tm6109 , tm2984 , tm6232 , tm10075 Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans.
Silkworms d17 Recognition of pathogen-derived sphingolipids in Arabidopsis.
Human and Animal Cells HeLa , LNCap.FGC(RCB2144) TBK1 inhibitors enhance transfection efficiency by suppressing p62/SQSTM1 phosphorylation.
Yeast FY18665 Environmental control of Pub1 (NEDD4 family E3 ligase) in Schizosaccharomyces pombe is regulated by TORC2 and Gsk3.
Drosophila The Integrator complex desensitizes cellular response to TGF-β/BMP signaling.
Drosophila 10010Ab-1 , 10014Ab-1 Maelstrom coordinates microtubule organization during Drosophila oogenesis through interaction with components of the MTOC.
C.intestinalis / (O.japonicus) Wild C. int Multidimensional analysis of uncharacterized sperm proteins in Ciona intestinalis: EST-based analysis and functional immunoscreening of testis-expressed genes.
Yeast pNHK53, pMK152 Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts.
Human and Animal Cells PC-12(RCB0009) Inhibition of the RhoA/Rho kinase system attenuates catecholamine biosynthesis in PC 12 rat pheochromocytoma cells.
Human and Animal Cells A549 , DU145(RCB2143) , PC-3(RCB2145) , PANC-1(RCB2145) , GI-1(RCB0763) , A431 , MCF7(RCB1904) Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly.
Arabidopsis / Cultured plant cells, genes pda15493 , pda13561 Phosphorylation of MAP65-1 by Arabidopsis Aurora Kinases Is Required for Efficient Cell Cycle Progression.
Human and Animal Cells SAS(RCB1974) Novel acridine-based N-acyl-homoserine lactone analogs induce endoreduplication in the human oral squamous carcinoma cell line SAS.
Human and Animal Cells HeLa(RCB0007) DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells.