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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Proteolysis*)
生物種 リソース名 タイトル
遺伝子材料 pCAGGS (RDB08938) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) An interactome-based framework for DDB1- and CUL4-associated factor prioritization in targeted protein degradation.
ショウジョウバエ DGRC#140919 ABHD18 degrades cardiolipin by stepwise hydrolysis of fatty acids.
ヒト・動物細胞 , 実験動物マウス MC3T3-E1(RCB1126) , RBRC05524 Phosphorylation-dependent osterix degradation negatively regulates osteoblast differentiation.
ヒト・動物細胞 293T(RCB2202) , Jurkat(RCB0806) Cell-type specific, inducible and acute degradation of targeted protein in mice by two degron systems.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) An IMiD-induced SALL4 degron system for selective degradation of target proteins.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) CRL2KLHDC3 and CRL1Fbxw7 cooperatively mediate c-Myc degradation.
ショウジョウバエ HMS02033 , HMS02963 , DGRC#108920 , DGRC#105687 pVHL-mediated SMAD3 degradation suppresses TGF-β signaling.
遺伝子材料 pAID1.2-CMV-NmScarlet-mAID (RDB19226) , pAID1.2-EF1a-NmScarlet-mAID (RDB19227) , pAIDFA-CMV-NmScarlet-mAID (RDB19228) , pAIDFA-EF1a-NmScarlet-mAID (RDB19229) , pAID1.2-CMV-linearizing in pX330 (RDB19230) , pAID-EF1a- linearizing in pX330 (RDB19231) A super-sensitive auxin-inducible degron system with an engineered auxin-TIR1 pair.
ヒト・動物細胞 RAW 264(RCB0535) Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes.
酵母 FY31941 Regulation of inorganic polyphosphate is required for proper vacuolar proteolysis in fission yeast.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Impaired proteolysis underlies autophagic dysfunction in Niemann-Pick type C disease.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Tau phosphorylation affects its axonal transport and degradation.
遺伝子材料 , ヒト・動物細胞 pCMV-VSV-G (RDB04392) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) , HCT116(RCB2979) Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane.
ショウジョウバエ An N-terminal di-proline motif is essential for fatty acid-dependent degradation of Δ9-desaturase in Drosophila.
ヒト・動物細胞 MG6(RCB2403) Nucleus distribution of cathepsin B in senescent microglia promotes brain aging through degradation of sirtuins.
線虫 tm1969 , tm2027 The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C.
原核生物(大腸菌) Keio collection Degp degrades a wide range of substrate proteins in Escherichia coli under stress conditions.
ヒト・動物細胞 T98G(RCB1954) High cell density increases glioblastoma cell viability under glucose deprivation via degradation of the cystine/glutamate transporter xCT (SLC7A11).
ヒト・動物細胞 ATDC5(RCB0565) Secreted tyrosine kinase Vlk negatively regulates Hedgehog signaling by inducing lysosomal degradation of Smoothened.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) The N-Degron Pathway Mediates ER-phagy.