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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins / genetics)
Species Resource Title
Human and Animal Cells TE-1(RCB1894) , TE-10(RCB2099) Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus.
Human and Animal Cells Jurkat Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Human and Animal Cells Ba/F3 NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations.
Human and Animal Cells Sa3(RCB0980) , SAS(RCB1974) Identification of Tumor-Suppressive miR-30e-3p Targets: Involvement of SERPINE1 in the Molecular Pathogenesis of Head and Neck Squamous Cell Carcinoma.
Human and Animal Cells PC-9(RCB4455) MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements.
Human and Animal Cells HeLaS3 , COS-7(RCB0539) BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.
Human and Animal Cells Kato III(RCB2088) , MKN28(RCB1000) , MKN45(RCB1001) Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer.
Human and Animal Cells 32D(RCB1145) In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
Drosophila Refinement of wingless expression by a wingless- and notch-responsive homeodomain protein, defective proventriculus.
Human and Animal Cells HeLa/Fucci(RCB2812) PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.
Human and Animal Cells IMR-32(RCB1895) NeuroD1 promotes neuroblastoma cell growth by inducing the expression of ALK.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CS-RfA-CG (RDB04390) , pENTR4-H1 (RDB04395) 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax.
Human and Animal Cells Hep G2(RCB1648) , HuH-7(RCB1366) The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma.
Human and Animal Cells 293T(RCB2202) , Jurkat Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.
Human and Animal Cells PANC-1(RCB2095) The centriole protein CEP76 negatively regulates PLK1 activity in the cytoplasm for proper mitotic progression.
Human and Animal Cells HS-Sch-2(RCB2230) , YST-1(RCB2136) , HS-PSS(RCB2362) Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Human and Animal Cells Ba/F3(RCB0805) TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
Human and Animal Cells TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) , TGBC1TKB(RCB1129) , TGBC2TKB(RCB1130) miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer.
DNA material pET30c-streptag-TET2 (RDB18377) Quantification of global DNA methylation level using 5-methylcytosine dioxygenase.