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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins / genetics)
Species Resource Title
Human and Animal Cells HeLaS3 , COS-7(RCB0539) BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.
Human and Animal Cells Kato III(RCB2088) , MKN28(RCB1000) , MKN45(RCB1001) Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer.
Human and Animal Cells 32D(RCB1145) In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
Drosophila Refinement of wingless expression by a wingless- and notch-responsive homeodomain protein, defective proventriculus.
Human and Animal Cells HeLa/Fucci(RCB2812) PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.
Human and Animal Cells IMR-32(RCB1895) NeuroD1 promotes neuroblastoma cell growth by inducing the expression of ALK.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CS-RfA-CG (RDB04390) , pENTR4-H1 (RDB04395) 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax.
Human and Animal Cells 293T(RCB2202) , Jurkat Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.
Human and Animal Cells PANC-1(RCB2095) The centriole protein CEP76 negatively regulates PLK1 activity in the cytoplasm for proper mitotic progression.
Human and Animal Cells HS-Sch-2(RCB2230) , YST-1(RCB2136) , HS-PSS(RCB2362) Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Human and Animal Cells Ba/F3(RCB0805) TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
Human and Animal Cells TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) , TGBC1TKB(RCB1129) , TGBC2TKB(RCB1130) miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer.
Human and Animal Cells MKN7(RCB0999) TET2 functions as a resistance factor against DNA methylation acquisition during Epstein-Barr virus infection.
Human and Animal Cells NCC-RbC-60(RCB2213) , NCC-RbC-83(RCB2217) , NCC-RbC-54(RCB2208) Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway.
Human and Animal Cells KGN(RCB1154) Identification of altered microRNAs and mRNAs in the cumulus cells of PCOS patients: miRNA-509-3p promotes oestradiol secretion by targeting MAP3K8.
Human and Animal Cells NIH3T3 Expression of Krüppel-like factor 6, KLF6, in rat pituitary stem/progenitor cells and its regulation of the PRRX2 gene.
Human and Animal Cells Ba/F3(RCB0805) , 32D(RCB1145) Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain.
Human and Animal Cells HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
Human and Animal Cells ATDC5(RCB0565) Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5.